Evidence map›Paper›PMID 28427084›Full record

Trial reportBritish journal of cancer2017

Long-term improvement of breast cancer survivors' quality of life by a 2-week group physical and educational intervention: 5-year update of the 'PACThe' trial.

Fabrice Kwiatkowski, Marie-Ange Mouret-Reynier, Martine Duclos, François Bridon, Thierry Hanh, Isabelle Van Praagh-Doreau, Armelle Travade, Marie-Paule Vasson, Sylvie Jouvency, Christian Roques and 1 more

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in British journal of cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05433077 (Real Life Pacthe), which is not on this map. Cited by 22 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05433077 active not recruitingnot on this mapstarted 2022, after this paper: background citation

Real Life Pacthe : Support and Post-therapeutic Rehabilitation for Women in Complete Remission of Breast Cancer in a Thermal Environment

TypeobservationalSponsorCentre Jean PerrinRan2022 to 2025Enrolled400ConditionsNon-Metastatic Breast Carcinoma, Remission, Quality of Life
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Body weight management in overweight and obese breast cancer survivors.The Cochrane database of systematic reviews · 2020
    Pooled it
  6. Dietary interventions for adult cancer survivors.The Cochrane database of systematic reviews · 2019
    Pooled it
  7. Article
  8. Beyond cancer treatment: dermo-aesthetic and other wellness recommendations for breast cancer patients.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Lifestyle Factors and Cancer: A Narrative Review.Mayo Clinic proceedings. Innovations, quality & outcomes · 2024
    Article
  13. Article
  14. Observational
  15. Importance of the duration of treatment in Balneotherapy.International journal of biometeorology · 2021
    Article
  16. Physical activity status in relation to quality of life and dietary habits in breast cancer survivors: subset analyses of KROG 14-09 nationwide questionnaire study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fabrice KwiatkowskiDepartment of Clinical Research, Comprehensive Anticancer Centre Jean Perrin, 58, rue Montalembert, 63011 Clermont-Ferrand, France.
Marie-Ange Mouret-ReynierDepartment of Oncology, Comprehensive Anticancer Centre Jean Perrin, 58, rue Montalembert, 63011 Clermont-Ferrand, France.
Martine DuclosDepartment of Sport Medicine and Functional Explorations, Gabriel Montpied University Hospital, Place Henri Dunant, 63000 Clermont-Ferrand, France.
François BridonInstitut de Formation des Masseurs-Kinésithérapeutes, Centre Hospitalier Lacarin, 3 Boulevard Denière, 03200 Vichy, France.
Thierry HanhCentre Nutritionnel de Vichy, 111 Boulevard des États Unis, 03200 Vichy, France.
Isabelle Van Praagh-DoreauDepartment of Oncology, Comprehensive Anticancer Centre Jean Perrin, 58, rue Montalembert, 63011 Clermont-Ferrand, France.
Armelle TravadeDepartment of Senology, Centre République, 99 avenue de la République, 63000 Clermont-Ferrand, France.
Marie-Paule VassonDepartment of Nutrition, Comprehensive Anticancer Centre Jean Perrin, 58, rue Montalembert, 63011 Clermont-Ferrand, France.
Sylvie JouvencyDepartment of Nutrition, Comprehensive Anticancer Centre Jean Perrin, 58, rue Montalembert, 63011 Clermont-Ferrand, France.
Christian RoquesUniversity of Toulouse, Physical and Rehabilitation Medicine, 31059 Toulouse, France.
Yves-Jean BignonDepartment of Oncogenetics, Comprehensive Anticancer Centre Jean Perrin, 58, rue Montalembert, 63011 Clermont-Ferrand, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe advantages of adapted physical activity and nutritional education (APANE) on breast cancer prognosis and quality of life (QoL) are well known, but long-term results are lacking.

methodsA randomised controlled trial testing a 2-week intervention in hydrothermal centres including APANE enrolled 251 patients post-chemotherapy. QoL and weight control were significantly improved at 12 months. A 5-year follow-up was performed to evaluate the persistence of improvements.

resultsQoL increase (SF36) was persistent: effect-size at 2, 3, 4 and 5 years equalled respectively 0.27 (-0.01; 0.56), 0.28 (-0.02; 0.58), 0.41 (0.02; 0.81) and 0.45 (0.11; 0.80). Weight control observed after intervention lasted 2 years: 2.7% decrease at 1 year (P=0.0085), 2.5% at 2 years (P=0.025); and respectively for waist -2.4% (-3.6; -1.1) (P=0.000014) and -1.3% (-2.5; -0.1) (P=0.0072).

conclusionsA 2-week intervention in hydrothermal centres performed shortly after chemotherapy can durably improve breast cancer patients' QoL and reduce weight.

Indexed as

DietExercisePatient Education as TopicQuality of LifeSurvivorsAdolescentAdultAgedAnxietyBody WeightBreast NeoplasmsDepressionFemaleHumansMiddle AgedSurveys and Questionnaires

Identifiers

PMID28427084
PMCPMC5520091

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.