ArticlePloS one2017
Genome-wide identification and characterization of miRNAome from tomato (Solanum lycopersicum) roots and root-knot nematode (Meloidogyne incognita) during susceptible interaction.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 57 citations in OpenAlex.
- Environmental sex determination in the cyst nematode Globodera pallida defaults to male development.BMC biology · 2026Article
- miRNA-Mediated Regulation ofInternational journal of molecular sciences · 2025Article
- MicroRNA gatekeepers: Orchestrating rhizospheric dynamics.Journal of integrative plant biology · 2025Review
- MicroRNAs in plant-parasitic nematodes: what are they and why should we care?Journal of nematology · 2025Review
- Unraveling the enigma of root-knot nematodes: from origins to advanced management strategies in agriculture.Planta · 2024Review
- Exploring the putative microRNAs cross-kingdom transfer inFrontiers in plant science · 2024Article
- Small RNAs: Efficient and miraculous effectors that play key roles in plant-microbe interactions.Molecular plant pathology · 2023Review
- Tomato MicroRNAs and Their Functions.International journal of molecular sciences · 2022Review
- miR778 mediates gene expression, histone modification, and DNA methylation during cyst nematode parasitism.Plant physiology · 2022Article
- Article
- Elucidating micro RNAs role in different plant-pathogen interactions.Molecular biology reports · 2020Review
- Genome-Wide Screening and Characterization of Non-Coding RNAs inNon-coding RNA · 2020Article
- Chitin Biosynthesis Inhibition ofInternational journal of molecular sciences · 2020Article
- Identification of MicroRNAs That Respond to Soybean Cyst Nematode Infection in Early Stages in Resistant and Susceptible Soybean Cultivars.International journal of molecular sciences · 2019Article
- The Tomato Translational Landscape Revealed by Transcriptome Assembly and Ribosome Profiling.Plant physiology · 2019Article
- Identification and expression profiling of miRNAs in two color variants of carrot (Daucus carota L.) using deep sequencing.PloS one · 2019Article
- MicroRNAs, New Players in the Plant-Nematode Interaction.Frontiers in plant science · 2019Review
- Silenced retrotransposons are major rasiRNAs targets in Arabidopsis galls induced by Meloidogyne javanica.Molecular plant pathology · 2018Article
- Signal Transduction in Plant⁻Nematode Interactions.International journal of molecular sciences · 2018Review
- The phenotypic and molecular assessment of the non-conserved Arabidopsis MICRORNA163/S-ADENOSYL-METHYLTRANSFERASE regulatory module during biotic stress.Molecular genetics and genomics : MGG · 2018Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Root-knot nematodes (RKNs, Meloidogyne spp.) are the most damaging plant parasites causing severe losses to crop production. The present study reports genome-wide identification and characterization of both tomato and RKN miRNAs simultaneously from RKN-infected susceptible tomato roots using high-throughput sequencing technique. RNAseq data from 11 small RNA libraries derived from 5 disease development stages identified 281 novel miRNAs of tomato in addition to 52 conserved and 4 variants of conserved miRNAs. Additionally, the same set of RNAseq data identified 38 conserved and 290 novel RKN miRNAs. Both tomato and RKN miRNAs showed differential expression at 5 stages of disease development based on digital expression profiles. In tomato, further validation through qRT-PCR confirmed that majority of miRNAs were significantly upregulated during susceptible response whereas downregulated during resistance response. The predicted targets of 8 conserved and 1 novel miRNAs were validated through 5'RLM-RACE. A negative correlation between expression profiles of a few conserved miRNAs (miR156, miR159, miR164 and miR396) and their targets (SBP, GAMYB-like, NAC and GRF1 transcription factor) was confirmed. A novel Sly_miRNA996 also showed a negative correlation with its target MYB-like transcription factor. These results indicate that the conserved and novel tomato miRNAs are involved in regulating developmental changes in host root during RKN infection. In RKN, the targets of conserved miRNAs were also predicted and a few of their predicted target genes are known to be involved in nematode parasitism. Further, the potential roles of both tomato and RKN miRNAs have been discussed.
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