ReviewCurrent opinion in psychiatry2017
Sex differences in prescription opioid use.
Review in Current opinion in psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 153 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
153 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Treatment Outcomes in Patients With Opioid Use Disorder Who Were First Introduced to Opioids by Prescription: A Systematic Review and Meta-Analysis.Frontiers in psychiatry · 2020Pooled it
- Sex differences in the response to opioids for pain relief: A systematic review and meta-analysis.Pharmacological research · 2019Pooled it
- Can neuroimaging help combat the opioid epidemic? A systematic review of clinical and pharmacological challenge fMRI studies with recommendations for future research.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Pooled it
- 6-week cryo-compression therapy and opioid use after unicompartmental knee arthroplasty with comparable pain scores: a secondary analysis of a randomized controlled trial.Acta orthopaedica · 2026Trial
- Patient, Provider, and Clinic Characteristics Associated with Opioid and Non-Opioid Pain Prescriptions for Patients Receiving Low Back Imaging in Primary Care.Journal of the American Board of Family Medicine : JABFMTrial
- Young adult polysubstance use trajectories and later non-prescribed opioid use and drug use disorder symptoms: A propensity score-matched analysis.Drug and alcohol dependence reports · 2026Article
- Opioid and Methadone Prescribing for Infants with Surgical Management of Congenital Heart Disease.Pediatric cardiology · 2026Observational
- Acute glucagon-like peptide-1 receptor agonist, semaglutide, attenuates cue-, drug-, and stress-induced fentanyl seeking in male Sprague-Dawley rats.Behavioural pharmacology · 2026Article
- Gastrointestinal symptoms, faecal short-chain fatty acids and dietary intake in older adults: the Hordaland Health Study 3.European journal of nutrition · 2026Article
- Fentanyl Utilization During Extracorporeal Membrane Oxygenation and Risk of Methadone Treatment Among Pediatric ECMO Survivors.Pediatric surgery international · 2026Article
- Age, sex, and ethnic differences in substance use and/or substance use disorders among runaway and homeless youth: A meta-analysis and meta-regression.European child & adolescent psychiatry · 2026Review
- Trends in the dispensing of opioids for pain and concurrent benzodiazepine use among First Nations People in Ontario, Canada, from 2013 to 2021.Canadian journal of public health = Revue canadienne de sante publique · 2026Article
- Comparison of Opioid Utilization in Older Adults with Rheumatoid Arthritis before and after Initiating Biological or Targeted Synthetic Disease-Modifying Antirheumatic Drugs.Drugs - real world outcomes · 2026Article
- Opioid dispensing prior to opioid toxicity hospitalizations and emergency department visits in Canada, 2018-2022.PloS one · 2026Article
- The evolving epidemiology of opioid use disorder: polysubstance use, drug supply transformation, and policy implications.Frontiers in public health · 2026Review
- Review
- Opioids and Respiratory Related Consequences.Sleep medicine clinics · 2025Review
- Role of Pain in Adults Undergoing Soft Tissue and Maxillomandibular Advancement Surgery for Obstructive Sleep Apnea.Laryngoscope investigative otolaryngology · 2025Article
- Risks for Adverse Events by Sex and Age After Prescription Opioid Dose Reduction: A Secondary Analysis Across 8 U.S. Health Systems.American journal of preventive medicine · 2025Observational
- Oxycodone self-administration and drug-primed responding in male and female squirrel monkeys: Effects of alternative reinforcer availability.The Journal of pharmacology and experimental therapeutics · 2025Article
93 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
purpose of reviewRecent literature focused on prescription opioids has neglected sex differences in use. Here, we evaluated the recent literature (since 2015) examining sex differences in prescription opioid use. RECENT
findingsBetween 2015 and 2016, our review found only eight articles addressing sex differences in prescription opioid use mostly opioid misuse in North America among individuals with chronic pain. Risk factors included depression, pain, and polydrug use. In addition to that review, we had the opportunity to further address sex differences in, and risk factors for, prescription opioid use through a community engagement program, HealthStreet. Among the sample (n = 8525, Mage = 43.7 years, 58.6% women), approximately half reported use of prescription opioids. Women were significantly more likely to report lifetime use (54.9 vs. 42.2%; P < 0.0001) and report cancer compared with men, yet, women with cancer had a significantly reduced risk of using opioids compared with men with cancer (odds ratio: 0.46; 95% confidence interval, 0.36-0.59). SUMMARY: Only a few recently published studies analyzed sex differences related to prescription opioid use. Findings from the literature and our data suggest women are more likely to use prescription opioids compared with men. There is limited information on sex differences in opioid use risk factors and outcomes and more research in this area is warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.