Evidence map›Paper›PMID 28426462›Full record

ReviewCurrent opinion in gastroenterology2017

High-resolution esophageal manometry: interpretation in clinical practice.

Rena Yadlapati

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Current opinion in gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06314893 terminatednot on this mapstarted 2022, after this paper: background citation

Correlation of High Resolution Manometry and Upper Gastrointestinal Marshmallow Study in Preoperative Esophageal Motility Assessment

TypeobservationalSponsorLexington Health IncorporatedRan2022 to 2025Enrolled204ConditionsEsophageal Motility Disorders
NCT06973070 completednot on this mapstarted 2025, after this paper: background citation

Utilization of Upper GI Marshmallow Series Versus High Resolution Manometry in Preoperative Esophageal Motility Assessment

TypeobservationalSponsorLexington Health IncorporatedRan2025 to 2025Enrolled204ConditionsGERD (Gastroesophageal Reflux Disease)
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Supragastric belching: Evaluating the efficacy of short-term Ryle's tube placement and diaphragmatic breathing technique.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  6. Article
  7. Esophageal motility disorders other than achalasia.Abdominal radiology (New York) · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. The Saudi Gastroenterology Association consensus on the clinical care pathway for the diagnosis and treatment of GERD.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Rena YadlapatiDivision of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Funding

Training Grant in Gastrointestinal Physiology and PsychologyT32DK101363 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PANDOLFINO, JOHN E · 2014 to 2018
$1.2M
NIDDK NIH HHS T32 DK101363
6 · The paper itself

Abstract

purpose of reviewEsophageal high-resolution manometry (HRM) is the current state-of-the-art diagnostic tool to evaluate esophageal motility patterns and, as such, is widely adopted in clinical practice. This article will review the interpretation of esophageal HRM in clinical practice. RECENT

findingsHRM uses a high-resolution catheter to transmit intraluminal pressure data that are subsequently converted into dynamic esophageal pressure topography (EPT) plots. Metric data from EPT plots are synthesized to yield an esophageal motility diagnosis according to the Chicago Classification, a formal analytic scheme for esophageal motility disorders, which is currently in version 3.0. The standard HRM protocol consists of a baseline phase and a series of 10 wet swallows in the supine or reclined position. In addition, data from swallows in the seated position and provocative HRM maneuvers provide useful information about motility properties. Combined high-resolution impedance technology is also clinically available and enables concurrent assessment of bolus transit and postprandial responses. Finally, there is ongoing interest to optimize the training and competency assessment for interpretation of HRM in clinical practice. SUMMARY: Esophageal HRM is a valuable and sophisticated clinical tool to evaluate esophageal motility patterns. Emerging clinical applications of esophageal HRM include combined impedance technology, provocative maneuvers, and postprandial evaluation.

Indexed as

Image Interpretation, Computer-AssistedManometryEsophageal Motility DisordersEsophagusHumansObserver VariationPeristalsisPractice Guidelines as TopicReproducibility of Results

Identifiers

PMID28426462
PMCPMC5568812

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.