Evidence map›Paper›PMID 28426440›Full record

Observational studyJournal of acquired immune deficiency syndromes (1999)2017

The Impact of Couple HIV Testing and Counseling on Consistent Condom Use Among Pregnant Women and Their Male Partners: An Observational Study.

Nora E Rosenberg, Lauren A Graybill, Austin Wesevich, Nuala McGrath, Carol E Golin, Suzanne Maman, Nivedita Bhushan, Mercy Tsidya, Limbikani Chimndozi, Irving F Hoffman and 2 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of acquired immune deficiency syndromes (1999), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  4. Results of a Couples-Based Randomized Controlled Trial Aimed to Increase Testing for HIV.Journal of acquired immune deficiency syndromes (1999) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Nora E Rosenberg*UNC Project, University of North Carolina at Chapel Hill, Lilongwe, Malawi; †School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; ‡Departments of Epidemiology and Health Behavior, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC; §Faculty of Medicine and Faculty of Social, Human, and Mathematical Sciences, University of Southampton, Southampton, United Kingdom; and ‖Department of Epidemiology, Ohio State University, Columbus, OH.
Lauren A Graybill
Austin Wesevich
Nuala McGrath
Carol E Golin
Suzanne Maman
Nivedita Bhushan
Mercy Tsidya
Limbikani Chimndozi
Irving F Hoffman
Mina C Hosseinipour
William C Miller
University of North Carolina at Chapel Hill · USUniversity of Southampton · GB

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Fogarty Global Health Fellows Coordinating CenterR25TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2012 to 2016
$6.9M
Training Program in Reproductive, Perinatal, and Pediatric EpidemiologyT32HD052468 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Julie L Daniels · 2008 to 2026
$3.8M
A dyad approach to combination HIV prevention in pregnancy for Zambia and MalawiR01AI131060 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H., MUTALE, WILBROAD · 2017 to 2020
$2.7M
Developing and Assessing a Male Engagement Intervention for Option B+ in MalawiR00MH104154 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROSENBERG, NORA · 2017 to 2019
$746k
Developing and Assessing a Male Engagement Intervention for Option B+ in MalawiK99MH104154 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROSENBERG, NORA · 2015 to 2016
$168k
FIC NIH HHS R25 TW009340NIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI131060NICHD NIH HHS T32 HD052468NIMH NIH HHS K99 MH104154NIMH NIH HHS R00 MH104154
6 · The paper itself

Abstract

backgroundIn sub-Saharan Africa couple HIV testing and counseling (CHTC) has been associated with substantial increases in safe sex, especially when at least one partner is HIV infected. However, this relationship has not been characterized in an Option B+ context.

settingThe study was conducted at the antenatal clinic at Bwaila District Hospital in Lilongwe, Malawi in 2016 under an Option B+ program.

methodsNinety heterosexual couples with an HIV-infected pregnant woman (female-positive couples) and 47 couples with an HIV-uninfected pregnant woman (female-negative couples) were enrolled in an observational study. Each couple member was assessed immediately before and 1 month after CHTC for safe sex (abstinence or consistent condom use in the last month). Generalized estimating equations were used to model change in safe sex before and after CHTC and to compare safe sex between female-positive and female-negative couples.

resultsMean age was 26 years among women and 32 years among men. Before CHTC, safe sex was comparable among female-positive couples (8%) and female-negative couples (2%) [risk ratio (RR): 3.7, 95% confidence interval (CI): 0.5 to 29.8]. One month after CHTC, safe sex was higher among female-positive couples (75%) than among female-negative couples (3%) (RR: 30.0, 95% CI: 4.3 to 207.7). Safe sex increased substantially after CTHC for female-positive couples (RR 9.6, 95% CI: 4.6 to 20.0), but not for female-negative couples (RR: 1.2, 95% CI: 0.1 to 18.7).

conclusionsEngaging pregnant couples in CHTC can have prevention benefits for couples with an HIV-infected pregnant woman, but additional prevention approaches may be needed for couples with an HIV-uninfected pregnant woman.

Indexed as

Directive CounselingMass ScreeningPrenatal CareAdolescentAdultCondomsDisease Transmission, InfectiousFamily CharacteristicsFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalMalawiMalePatient Acceptance of Health CarePregnancy

Identifiers

PMID28426440
PMCPMC5493523
OpenAlexW2606746690

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.