Evidence map›Paper›PMID 28425851›Full record

ReviewAdipocyte2017

Altered structure and function of adipose tissue in long-lived mice with growth hormone-related mutations.

Justin Darcy, Samuel McFadden, Andrzej Bartke

Open access · goldAbstract readReview
In one paragraph

Review in Adipocyte, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. microRNA-449a reduces growth hormone-stimulated senescent cell burden through PI3K-mTOR signaling.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Review
  7. Review
  8. Mouse models of growth hormone deficiency.Reviews in endocrine & metabolic disorders · 2021
    Review
  9. Article
  10. How Inflammation Blunts Innate Immunity in Aging.Interdisciplinary topics in gerontology and geriatrics · 2020
    Review
  11. Biomaterials to Mimic and Heal Connective Tissues.Advanced materials (Deerfield Beach, Fla.) · 2019
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Justin Darcya Department of Internal Medicine , Southern Illinois University School of Medicine , Springfield , Illinois , USA.ORCID 0000-0002-0657-3059
Samuel McFaddena Department of Internal Medicine , Southern Illinois University School of Medicine , Springfield , Illinois , USA.ORCID 0000-0002-2289-5066
Andrzej Bartkea Department of Internal Medicine , Southern Illinois University School of Medicine , Springfield , Illinois , USA.ORCID 0000-0002-2569-557X
Southern Illinois University School of Medicine · US

Funding

Longevity genes and calorie restriction: early post-natal effectsR01AG019899 · NIA · SOUTHERN ILLINOIS UNIVERSITY SCH OF MED · PI BARTKE, ANDRZEJ · 2001 to 2016
$6.1M
Aging at Thermoneutral TemperatureR21AG051869 · NIA · SOUTHERN ILLINOIS UNIVERSITY SCH OF MED · PI BARTKE, ANDRZEJ · 2016 to 2018
$490k
NIA NIH HHS R01 AG019899NIA NIH HHS R21 AG051869
6 · The paper itself

Abstract

A major focus of biogerontology is elucidating the role(s) of the endocrine system in aging and the accumulation of age-related diseases. Endocrine control of mammalian longevity was first reported in Ames dwarf (Prop1

Indexed as

Adipose TissueAdipose Tissue, BrownAdipose Tissue, WhiteAgingAnimalsBody CompositionCarrier ProteinsGrowth HormoneInsulin-Like Growth Factor IInsulin ResistanceLongevityMiceMice, KnockoutMice, TransgenicMutationProlactinCarrier ProteinsGrowth HormoneInsulin-Like Growth Factor IProlactinReceptors, Somatotropinsomatotropin-binding proteinagingAmes dwarfbGHbrown adipose tissueGHAGHR-KOgrowth hormoneSnell dwarfwhite adipose tissue

Identifiers

PMID28425851
PMCPMC5477739
OpenAlexW2599372888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.