Evidence map›Paper›PMID 28425841›Full record

ArticleAdipocyte2017

Adipocyte hypertrophy-hyperplasia balance contributes to weight loss after bariatric surgery.

Lindsey A Muir, Nicki A Baker, Alexandra R Washabaugh, Christopher K Neeley, Carmen G Flesher, Jennifer B DelProposto, Lynn M Geletka, Amir A Ghaferi, Jonathan F Finks, Kanakadurga Singer and 3 more

Open access · goldAbstract read
In one paragraph

Article in Adipocyte, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. The Beneficial Effects of Stingless Bee Honey fromInternational journal of environmental research and public health · 2019
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Lindsey A Muira Department of Pediatrics and Communicable Diseases , University of Michigan Medical School , Ann Arbor , MI , USA.
Nicki A Bakerb Department of Surgery , University of Michigan Medical School , Ann Arbor , MI , USA.
Alexandra R Washabaughb Department of Surgery , University of Michigan Medical School , Ann Arbor , MI , USA.
Christopher K Neeleyb Department of Surgery , University of Michigan Medical School , Ann Arbor , MI , USA.
Carmen G Flesherc Undergraduate Research Opportunity Program , University of Michigan , Ann Arbor , MI , USA.
Jennifer B DelPropostoa Department of Pediatrics and Communicable Diseases , University of Michigan Medical School , Ann Arbor , MI , USA.
Lynn M Geletkaa Department of Pediatrics and Communicable Diseases , University of Michigan Medical School , Ann Arbor , MI , USA.
Amir A Ghaferib Department of Surgery , University of Michigan Medical School , Ann Arbor , MI , USA.
Jonathan F Finksb Department of Surgery , University of Michigan Medical School , Ann Arbor , MI , USA.
Kanakadurga Singera Department of Pediatrics and Communicable Diseases , University of Michigan Medical School , Ann Arbor , MI , USA.
Oliver A Varbanb Department of Surgery , University of Michigan Medical School , Ann Arbor , MI , USA.
Carey N Lumenga Department of Pediatrics and Communicable Diseases , University of Michigan Medical School , Ann Arbor , MI , USA.
Robert W O'Rourkeb Department of Surgery , University of Michigan Medical School , Ann Arbor , MI , USA.
University of Michigan–Ann Arbor · US

Funding

Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Regulation of Adipose Tissue Inflammation By Antigen Presenting CellsR01DK090262 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, CAREY N · 2011 to 2024
$5.3M
Multidisciplinary Training Program in Basic Diabetes ResearchT32DK101357 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PETER ARVAN, Ormond A MacDougald · 2014 to 2026
$4.1M
Targeting hypoxia-inducible mediators to manipulate human adipocyte phenotypeR01DK097449 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI O'ROURKE, ROBERT W · 2013 to 2017
$1.7M
Mechanisms of hematopoietic stem cell activation in obesityK08DK101755 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SINGER, KANAKADURGA · 2015 to 2018
$644k
Regulation of lipid laden adipose tissue macrophages in metabolic dysfunctionF32DK105676 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MUIR, LINDSEY ALLISON · 2015 to 2016
$112k
NCATS NIH HHS UL1 TR000433NIDDK NIH HHS K08 DK101755NIDDK NIH HHS R01 DK097449NIDDK NIH HHS T32 DK101357
6 · The paper itself

Abstract

Predictors of weight loss responses are not well-defined. We hypothesized that adipose tissue phenotypic features related to remodeling would be associated with bariatric surgery weight loss responses. Visceral and subcutaneous adipose tissues collected from patients during bariatric surgery were studied with flow cytometry, immunohistochemistry, and QRTPCR, and results correlated with weight loss outcomes. Age, male sex, and a diagnosis of type 2 diabetes were associated with less weight loss. Adipocyte size was increased and preadipocyte frequency was decreased in visceral adipose tissue from diabetic subjects. Decreased adipose tissue preadipocyte frequency was associated with less weight loss in women but not men. These data suggest that phenotypic features of adipose tissue remodeling may predict responses to weight loss interventions.

Indexed as

AdipocytesAdipose TissueAdiposityBariatric SurgeryFemaleHumansHyperplasiaHypertrophyIntra-Abdominal FatMaleObesitySubcutaneous FatTreatment OutcomeWeight Lossadipose tissuebariatric surgerydiabeteshypertrophypreadipocyteweight loss

Identifiers

PMID28425841
PMCPMC5477697
OpenAlexW2581761891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.