Evidence map›Paper›PMID 28425576›Full record

ArticleStem cells translational medicine2017

Bone Marrow, Adipose, and Lung Tissue-Derived Murine Mesenchymal Stromal Cells Release Different Mediators and Differentially Affect Airway and Lung Parenchyma in Experimental Asthma.

Soraia C Abreu, Mariana A Antunes, Debora G Xisto, Fernanda F Cruz, Vivian C Branco, Elga Bandeira, Jamil Zola Kitoko, Almair F de Araújo, Ludmilla Dellatorre-Texeira, Priscilla C Olsen and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cells translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 82 citations in OpenAlex.

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  20. Host Defense againstJournal of immunology (Baltimore, Md. : 1950) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Soraia C AbreuLaboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University, Rio de Janeiro, Brazil.
Mariana A AntunesLaboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University, Rio de Janeiro, Brazil.
Debora G XistoLaboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University, Rio de Janeiro, Brazil.
Fernanda F CruzLaboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University, Rio de Janeiro, Brazil.
Vivian C BrancoLaboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University, Rio de Janeiro, Brazil.
Elga BandeiraLaboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University, Rio de Janeiro, Brazil.
Jamil Zola KitokoLaboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University, Rio de Janeiro, Brazil.
Almair F de AraújoLaboratory of Inflammation, Carlos Chagas Filho Institute of Biophysics, Federal University, Rio de Janeiro, Brazil.
Ludmilla Dellatorre-TexeiraLaboratory of Inflammation, Carlos Chagas Filho Institute of Biophysics, Federal University, Rio de Janeiro, Brazil.
Priscilla C OlsenLaboratory of Clinical Bacteriology and Immunology, School of Pharmacy, Federal University, Rio de Janeiro, Brazil.
Daniel J WeissDepartment of Medicine, University of Vermont, College of Medicine, Burlington, Vermont, USA.
Bruno L DiazLaboratory of Inflammation, Carlos Chagas Filho Institute of Biophysics, Federal University, Rio de Janeiro, Brazil.
Marcelo M MoralesLaboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Institute of Biophysics, Federal University, Rio de Janeiro, Brazil.
Patricia R M RoccoLaboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University, Rio de Janeiro, Brazil.ORCID 0000-0003-1412-7136
Czech Academy of Sciences, Institute of Biophysics · CZFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro · BRUniversidade Federal do Rio de Janeiro · BRUniversity of Vermont · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stromal cells (MSCs) from different sources have differential effects on lung injury. To compare the effects of murine MSCs from bone marrow (BM), adipose tissue (AD), and lung tissue (LUNG) on inflammatory and remodeling processes in experimental allergic asthma, female C57BL/6 mice were sensitized and challenged with ovalbumin (OVA) or saline (C). Twenty-four hours after the last challenge, mice received either saline (50 µl, SAL), BM-MSCs, AD-MSCs, or LUNG-MSCs (10

Indexed as

Adipose TissueAnimalsAsthmaBone Marrow CellsFemaleInflammation MediatorsLungMaleMesenchymal Stem CellsMesenchymal Stem Cell TransplantationMiceMice, Inbred C57BLTracheaInflammation MediatorsAsthmaFibrosisInflammationMacrophageMesenchymal stromal cells

Identifiers

PMID28425576
PMCPMC5689762
OpenAlexW2606259926

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.