ArticleScientific reports2017
Estimating the irreversible pressure drop across a stenosis by quantifying turbulence production using 4D Flow MRI.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Evaluation of the Haemodynamic Behaviour of Stenosed Aortic Heart Valves Using Fluid Structure Interaction Modelling.International journal for numerical methods in biomedical engineering · 2026Article
- Quantitative Evaluation of Carotid Artery Stenosis by Multi-VENC 4D Flow MRI: Incorporating Turbulent Kinetic Energy for Clinical Validity.Journal of magnetic resonance imaging : JMRI · 2025Article
- Non-invasive quantification of pressure drops in stenotic intracranial vessels: using deep learning-enhanced 4D flow MRI to characterize the regional haemodynamics of the pulsing brain.Interface focus · 2025Article
- Changes of intracardiac flow dynamics measured by HyperDoppler in patients with aortic stenosis.European heart journal open · 2024Article
- Optimizing encoding strategies for 4D Flow MRI of mean and turbulent flow.Scientific reports · 2024Article
- Assessing the impact of turbulent kinetic energy boundary conditions on turbulent flow simulations using computational fluid dynamics.Scientific reports · 2023Article
- Aortic Stenosis: Haemodynamic Benchmark and Metric Reliability Study.Journal of cardiovascular translational research · 2023Article
- A Protocol for Coupling Volumetrically Dynamic In-Vitro Experiments to Numerical Physiology Simulation for a Hybrid Cardiovascular Model.IEEE transactions on bio-medical engineering · 2023Article
- Non-invasive cardiovascular magnetic resonance assessment of pressure recovery distance after aortic valve stenosis.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Article
- Irregular anatomical features can alter hemodynamics in Takayasu arteritis.JVS-vascular science · 2023Article
- Synthesis of patient-specific multipoint 4D flow MRI data of turbulent aortic flow downstream of stenotic valves.Scientific reports · 2022Article
- On the numerical treatment of viscous and convective effects in relative pressure reconstruction methods.International journal for numerical methods in biomedical engineering · 2022Article
- Divergence-Free Constrained Phase Unwrapping and Denoising for 4D Flow MRI Using Weighted Least-Squares.IEEE transactions on medical imaging · 2021Article
- Analysis of Turbulence Effects in a Patient-Specific Aorta with Aortic Valve Stenosis.Cardiovascular engineering and technology · 2021Article
- The effect of coarctation degrees on wall shear stress indices.Scientific reports · 2021Article
- Characterization of anisotropic turbulence behavior in pulsatile blood flow.Biomechanics and modeling in mechanobiology · 2021Article
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- Investigation of phase-contrast magnetic resonance imaging underestimation of turbulent flow through the aortic valve phantom: experimental and computational study using lattice Boltzmann method.Magma (New York, N.Y.) · 2020Article
- Pathologic Shear and Elongation Rates Do Not Cause Cleavage of Von Willebrand Factor by ADAMTS13 in a Purified System.Cellular and molecular bioengineering · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The pressure drop across a stenotic vessel is an important parameter in medicine, providing a commonly used and intuitive metric for evaluating the severity of the stenosis. However, non-invasive estimation of the pressure drop under pathological conditions has remained difficult. This study demonstrates a novel method to quantify the irreversible pressure drop across a stenosis using 4D Flow MRI by calculating the total turbulence production of the flow. Simulation MRI acquisitions showed that the energy lost to turbulence production can be accurately quantified with 4D Flow MRI within a range of practical spatial resolutions (1-3 mm; regression slope = 0.91, R
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