SynthesisTransfusion medicine (Oxford, England)2017
Serum ferritin thresholds for the diagnosis of iron deficiency in pregnancy: a systematic review.
Synthesis in Transfusion medicine (Oxford, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 75 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Daily vs. Intermittent Iron Therapy in Iron Deficient Pregnant Patients: A Randomized Noninferiority Trial
Establishment of Reference Intervals for Iron Test Panel for Pregnant Women at Hung Vuong Hospital
Who cites it
75 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Guideline
- Daily oral iron supplementation during pregnancy.The Cochrane database of systematic reviews · 2024Pooled it
- Iron supplements in pregnant women with normal iron status: A systematic review and meta-analysis.Acta obstetricia et gynecologica Scandinavica · 2023Pooled it
- Maternal Iron Status in Pregnancy and Child Health Outcomes after Birth: A Systematic Review and Meta-Analysis.Nutrients · 2021Pooled it
- Impact of oral iron dosing regimens on iron biomarkers during pregnancy: insights from the PANDA trial.Blood advances · 2026Trial
- Intravenous ferric derisomaltose versus oral iron for persistent iron deficient pregnant women: a randomised controlled trial.Archives of gynecology and obstetrics · 2023Trial
- The effect of Lactiplantibacillus plantarum 299v together with a low dose of iron on iron status in healthy pregnant women: A randomized clinical trial.Acta obstetricia et gynecologica Scandinavica · 2021Trial
- Prediction of anemia at delivery.Scientific reports · 2021Trial
- Article
- Variation in antenatal anaemia guidelines across the NHS in the United Kingdom: A cross-sectional study.British journal of haematology · 2026Article
- Ferritin as a diagnostic point-of-care marker in iron deficiency anemia: a narrative review and clinical implications.Annals of translational medicine · 2026Review
- Cost-effectiveness of iron deficiency screening in pregnancy across ferritin-based thresholds.Blood advances · 2026Article
- Article
- Iron deficiency with and without anemia in pregnancy: A scoping review of prevalence and perinatal impact.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Physiologically based ferritin thresholds to redefine early pregnancy iron screening: a cross-sectional study.Scientific reports · 2026Article
- Article
- Recommendations of the AGG (Obstetrics Working Group, Section for Maternal Diseases) for the Management of Anemia in Pregnancy - Part 1 (Iron Deficiency Anemia).Geburtshilfe und Frauenheilkunde · 2025Article
- Exploring the Use of Iron and Hematologic Indicators for Surveillance of Iron Deficiency in Pregnant and Nonpregnant Women in the United States.The Journal of nutrition · 2025Article
- Association of Stress and Inflammatory Diseases with Serum Ferritin and Iron Concentrations in Neonatal Calves.Animals : an open access journal from MDPI · 2025Article
- Hematologic Complications of Pregnancy.European journal of haematology · 2025Review
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The aim of this review was to understand the landscape of serum ferritin in diagnosing iron deficiency in the aetiology of anaemia in pregnancy. Iron deficiency in pregnancy is a major public health problem leading to the development of anaemia. Reducing the global prevalence of anaemia in women of reproductive age is a 2025 global nutrition target. Bone marrow aspiration is the gold standard test for iron deficiency but requires an invasive procedure; therefore, serum ferritin is the most clinically useful test. We undertook a systematic search of electronic databases and trial registers from inception to January 2016. Studies of iron or micronutrient supplementation in pregnancy with pre-defined serum ferritin thresholds were included. Two independent reviewers selected studies, extracted data and assessed quality. There were 76 relevant studies mainly of observational study design (57%). The most commonly used thresholds of serum ferritin for the diagnosis of iron deficiency were <12 and <15 ng mL
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.