Evidence map›Paper›PMID 28425085›Full record

ArticleArchives of osteoporosis2017

UK clinical guideline for the prevention and treatment of osteoporosis.

J Compston, A Cooper, C Cooper, N Gittoes, C Gregson, N Harvey, S Hope, J A Kanis, E V McCloskey, K E S Poole and 6 more

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of osteoporosis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 391 papers, 19 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
391citing papers in PubMed, 19 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03930992 phase3completednot on this mapstarted 2019, after this paper: background citation

Efficacy of 4 mg Zoledronic Acid Plus Colaren vs 4mg Zoledronic Acid + Conventional Treatment for Secondary Osteoporosis in HIV Positive and Negative Men

TypeinterventionalSponsorUniversity of GuadalajaraRan2019 to 2022Enrolled30ConditionsSecondary OsteoporosisArmsColaren in HIV positive, standard treatment in HIV positive, Colaren in HIV negative, standard treatment in HIV negative
NCT06092775 unknown statusnot on this mapstarted 2023, after this paper: background citation

Prevalence of Subclinical Vertebral Fractures in Rheumatoid Arthritis and Ankylosing Spondylitis in Egyptian Patients and Its Relation to Some Clinical Data

TypeobservationalSponsorAssiut UniversityRan2023 to 2025Enrolled93ConditionsVertebral FractureArmsDEXA scan,X_ray
3 · Its place in the literature

Who cites it

391 citing papers in PubMed, 19 syntheses or guidelines pooled it.

  1. Guideline
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  6. Does adding exercise or physical activity to pharmacological osteoporosis therapy in patients with increased fracture risk improve bone mineral density and lower fracture risk? A systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023
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  14. Comparing medication adherence in patients receiving bisphosphonates for preventing fragility fractures: a comprehensive systematic review and network meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Pooled it
  15. Guideline
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  17. Augmenting Osteoporosis Imaging with Machine Learning.Current osteoporosis reports · 2021
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  20. Trial

331 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

J CompstonDepartment of Medicine, Cambridge Biomedical Campus, Cambridge, UK. jec1001@cam.ac.uk.
A CooperCrawley Fracture Liaison Service, Crawley, Sussex, UK.
C CooperMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
N GittoesUniversity Hospitals Birmingham NHS Foundation Trust, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham & Birmingham Health Partners, Birmingham, UK.
C GregsonMusculoskeletal Research Unit, University of Bristol and Royal United Hospital NHS Foundation Trust, Bath, UK.
N HarveyMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
S HopeMetabolic Bone, Nuffield Orthopaedic Hospital, Oxford, UK.
J A KanisCentre for Metabolic Diseases, University of Sheffield Medical School, Sheffield, UK.
E V McCloskeyMetabolic Bone, University of Sheffield, Sheffield, UK.
K E S PooleDepartment of Medicine, Cambridge Biomedical Campus, Cambridge, UK.
D M ReidEmeritus Professor of Rheumatology, University of Aberdeen, Aberdeen, UK.
P SelbyMetabolic Bone Disease, University of Manchester, Manchester, UK.
F ThompsonNational Osteoporosis Society, Camerton, UK.
A ThurstonNational Osteoporosis Society, Camerton, UK.
N VineDepartment of Medicine, Cambridge Biomedical Campus, Cambridge, UK.
National Osteoporosis Guideline Group (NOGG)

Funding

Arthritis Research UK 17702Arthritis Research UK 21231Department of Health HTA/10/33/04Medical Research Council G0400491Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UU_12011/1Versus Arthritis 17702Versus Arthritis 21231
6 · The paper itself

Abstract

introductionIn 2008, the UK National Osteoporosis Guideline Group (NOGG) produced a guideline on the prevention and treatment of osteoporosis, with an update in 2013. This paper presents a major update of the guideline, the scope of which is to review the assessment and management of osteoporosis and the prevention of fragility fractures in postmenopausal women and men age 50 years or over.

methodsWhere available, systematic reviews, meta-analyses and randomised controlled trials were used to provide the evidence base. Conclusions and recommendations were systematically graded according to the strength of the available evidence.

resultsReview of the evidence and recommendations are provided for the diagnosis of osteoporosis, fracture-risk assessment, lifestyle measures and pharmacological interventions, duration and monitoring of bisphosphonate therapy, glucocorticoid-induced osteoporosis, osteoporosis in men, postfracture care and intervention thresholds.

conclusionThe guideline, which has received accreditation from the National Institute of Health and Care Excellence (NICE), provides a comprehensive overview of the assessment and management of osteoporosis for all healthcare professionals who are involved in its management.

Indexed as

Practice Guidelines as TopicAgedBone Density Conservation AgentsDiphosphonatesFemaleHumansLife StyleMaleMiddle AgedOsteoporosisOsteoporotic FracturesRisk AssessmentUnited KingdomBone Density Conservation AgentsDiphosphonatesFractureGuidelineNOGGOsteoporosis

Identifiers

PMID28425085
PMCPMC5397452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.