Evidence map›Paper›PMID 28425083›Full record

ArticleSleep & breathing = Schlaf & Atmung2018

Restless legs syndrome/Willis-Ekbom disease prevalence in beta thalassemia patients.

Euthimia Dimitriadou, Christoforos D Giannaki, Maria Tsekoura, Ioannis Stefanidis, Georgios M Hadjigeorgiou, Eleftherios Lavdas, Christina Karatzaferi, Giorgos K Sakkas

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Euthimia DimitriadouDepartment of Haematology, General Hospital of Trikala, Trikala, Greece.
Christoforos D GiannakiDepartment of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus.
Maria TsekouraDepartment of PE and Sport Science, University of Thessaly, Trikala, Greece.
Ioannis StefanidisSchool of Health Science, Department of Medicine, University of Thessaly, Larissa, Greece.
Georgios M HadjigeorgiouSchool of Health Science, Department of Medicine, University of Thessaly, Larissa, Greece.
Eleftherios LavdasDepartment of Medical Radiological Technologists, Technological Education Institute of Athens, Athens, Greece.
Christina KaratzaferiDepartment of PE and Sport Science, University of Thessaly, Trikala, Greece.
Giorgos K SakkasDepartment of PE and Sport Science, University of Thessaly, Trikala, Greece. gsakkas@marjon.ac.cy.
University of Thessaly · GRPlymouth Marjon University · GBe-Trikala (Greece) · GRTechnological Educational Institute of Athens · GRUniversity of Nicosia · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBoth beta thalassemia and restless legs syndrome (RLS) patients share some common pathophysiological characteristics related to iron handling. In the present study, the aim was to explore the prevalence of RLS as well as to explore potential association between the syndrome and various quality of life-related parameters in a sample of beta thalassemia patients.

methodsOne hundred fourteen (age 40 ± 11 yr, 59 M/55F) beta thalassemia patients participated in this cross-sectional descriptive study. Patients were screened for RLS based on the international RLS study group diagnostic criteria as well as a battery of validated questionnaires.

resultsThe prevalence of RLS in this sample of beta thalassemia patients was zero. The quality of life score was low (78 ± 18). Iron levels were within normal range (191 ± 66 mcg/dL) while ferritin levels were high as expected (1836 ± 225 ng/dL).

conclusionsOur sample of patients comes from central Greece where the prevalence of RLS in the general population is 4% while in renal failure patients is 27%. To our surprise, there was no presence of RLS among this sample of beta thalassemia patients. The adequate levels of iron and ferritin often seen in these patients could be the reason of the absence of RLS symptoms.

Indexed as

AdolescentAdultAgedbeta-ThalassemiaCross-Sectional StudiesFemaleGreeceHumansMaleMiddle AgedPrevalenceQuality of LifeRestless Legs SyndromeYoung AdultAnemiaFerritinIronSleep disorders

Identifiers

PMID28425083
OpenAlexW2607284811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.