Evidence map›Paper›PMID 28425012›Full record

ArticleFish physiology and biochemistry2017

A study of the damage of the intestinal mucosa barrier structure and function of Ctenopharyngodon idella with Aeromonas hydrophila.

Wei-Guang Kong, Si-Si Li, Xiao-Xuan Chen, Yu-Qing Huang, Ying Tang, Zhi-Xin Wu

Abstract read
PubMed Publisher
In one paragraph

Article in Fish physiology and biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Detection and Identification ofPathogens (Basel, Switzerland) · 2026
    Article
  3. Isolation, Identification, and Characteristics ofPathogens (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. The impact ofMicrobiology spectrum · 2024
    Article
  8. Emerging role of vitamin DAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2024
    Article
  9. Article
  10. Vitamin D Promotes Mucosal Barrier System of Fish Skin Infected withInternational journal of molecular sciences · 2023
    Article
  11. Article
  12. An Update on the GenusMicroorganisms · 2020
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Wei-Guang KongDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, 430070, China.
Si-Si LiDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, 430070, China.
Xiao-Xuan ChenDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, 430070, China.
Yu-Qing HuangDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, 430070, China.
Ying TangDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, 430070, China.
Zhi-Xin WuDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, 430070, China. wuzhixin@mail.hzau.edu.cn.
Ministry of Agriculture and Rural Affairs · CNHuazhong Agricultural University · CNZhejiang Institute of Freshwater Fisheries · CN

Funding

National Natural Science Foundation of China (CN) NO.31472310
6 · The paper itself

Abstract

The aim of this study is to explore the effect of Aeromonas hydrophila on the intestinal mucosal barrier structure and intestinal permeability in grass carp (Ctenopharyngodon idella). Histopathological examinations showed that A. hydrophila induced severe intestinal lesions, including inflammatory cell infiltration and intestinal villus fusion and swelling. Messenger RNA (mRNA) expression of the inflammatory cytokines TNF-α, IL-1β, IL-8, IL-10 and MyD88 was significantly increased after infection with A. hydrophila. The permeability of intestinal mucosa was determined using Evans blue (EB) and D-lactic acid. The results indicated that the levels of EB and serum D-lactic acid were significantly increased after infection with A. hydrophila (p < 0.05). Our results also indicated that the intestinal mucosal barrier injury induced by A. hydrophila infection was closely associated with the expression of the tight junction (TJ) protein zonula occludens-1 (ZO-1), occludin, claudin b and claudin c as well as the activity of Na

Indexed as

Aeromonas hydrophilaAnimalsCarpsFish DiseasesGram-Negative Bacterial InfectionsIntestinal MucosaA. hydrophilaGrass carpInflammationIntestinePermeabilityTight junction

Identifiers

PMID28425012
OpenAlexW2607456087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.