Evidence map›Paper›PMID 28424908›Full record

Trial reportSurgical endoscopy2017

Delayed closure of open abdomen in septic patients treated with negative pressure wound therapy and dynamic fascial suture: the long-term follow-up study.

Anna Theresa Hofmann, Simone Gruber-Blum, Michael Lechner, Alexander Petter-Puchner, Karl Glaser, René Fortelny

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Anna Theresa HofmannDepartment of General, Visceral and Oncological Surgery, Wilhelminenspital, Montleartstrasse 37, 1160, Vienna, Austria. anna.hofmann@wienkav.at.ORCID 0000-0002-0178-5343
Simone Gruber-BlumDepartment of General, Visceral and Oncological Surgery, Wilhelminenspital, Montleartstrasse 37, 1160, Vienna, Austria.
Michael LechnerDepartment of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria.
Alexander Petter-PuchnerDepartment of General, Visceral and Oncological Surgery, Wilhelminenspital, Montleartstrasse 37, 1160, Vienna, Austria.
Karl GlaserDepartment of General, Visceral and Oncological Surgery, Wilhelminenspital, Montleartstrasse 37, 1160, Vienna, Austria.
René FortelnyDepartment of General, Visceral and Oncological Surgery, Wilhelminenspital, Montleartstrasse 37, 1160, Vienna, Austria.
Wilhelminen Hospital · ATParacelsus Medical University · ATSigmund Freud Privatuniversität Wien · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNegative pressure wound therapy (NPWT) is widely used in the treatment of open abdomen (OA). The use of dynamic fascial sutures (DFS) increases the rate of successful delayed closure by reducing fascial lateralization. We recently published a prospective controlled trial including 87 patients undergoing abdominal surgery for secondary peritonitis between 2007 and 2012. Patients were treated with NPWT and DFS for approximation of fascial edges. The present study represents a follow-up assessment of these patients 5-9 years after OA treatment with NPWT and DFS.

methodsThe 39 patients still alive were included in the recent study according to the protocol of our last study in 2013. All patients received a questionnaire regarding long-term complications after OA treatment between 2007 and 2012. Mean follow-up was 5-9 years. Analyzed parameters included pain, the presence of incisional hernia, and subsequent surgical interventions. Results were analyzed quantitatively.

resultsOne patient had deceased since the last publication in 2013, and hence 38 patients were included in the current study. The median age was 60.9 (25.2-86.1) years, and 17 (44.7%) were females. Overall 56.3% of the original 87 patients had died during the long-term follow-up period. 21 patients (55.3%) answered the questionnaire. Six (28.6%) declared that they suffered from pain in the previous operating field, five (23.8%) at rest, and three (14.3%) during exercise. In five patients (23.8%), pain lasted for more than 3 months. One patient (4.8%) still requires analgesic treatment. Among the 21 patients, seven (33.3%) were found to have incisional hernias. Three hernias (42.9%) were treated by surgery.

conclusionIncisional hernia rates after OA treatment remain high, but are accompanied by little pain. The ideal technique of fascial closure after NPWT should be investigated in further research.

Indexed as

Abdominal Wound Closure TechniquesAdultAgedAged, 80 and overFasciaFemaleFollow-Up StudiesHumansMaleMiddle AgedNegative-Pressure Wound TherapyPeritonitisPostoperative ComplicationsProspective StudiesSurgical MeshSurveys and QuestionnairesDelayed closureDynamic fascial sutureNegative pressure wound therapyOpen abdomenSecondary peritonitis

Identifiers

PMID28424908
OpenAlexW2607080724

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.