Evidence map›Paper›PMID 28424867›Full record

ArticleEuropean journal of nutrition2018

J-shaped relationship between habitual coffee consumption and 10-year (2002-2012) cardiovascular disease incidence: the ATTICA study.

Georgia-Maria Kouli, Demosthenes B Panagiotakos, Ekavi N Georgousopoulou, Duane D Mellor, Christina Chrysohoou, Adela Zana, Constantine Tsigos, Dimitrios Tousoulis, Christodoulos Stefanadis, Christos Pitsavos

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In one paragraph

Article in European journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Georgia-Maria KouliDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 46 Paleon Polemiston St., 166 74, Glyfada, Attica, Greece.
Demosthenes B PanagiotakosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 46 Paleon Polemiston St., 166 74, Glyfada, Attica, Greece. d.b.panagiotakos@usa.net.
Ekavi N GeorgousopoulouDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 46 Paleon Polemiston St., 166 74, Glyfada, Attica, Greece.
Duane D MellorFaculty of Health, University of Canberra, Canberra, ACT, Australia.
Christina ChrysohoouFirst Cardiology Clinic, School of Medicine, University of Athens, Athens, Greece.
Adela ZanaDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 46 Paleon Polemiston St., 166 74, Glyfada, Attica, Greece.
Constantine TsigosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 46 Paleon Polemiston St., 166 74, Glyfada, Attica, Greece.
Dimitrios TousoulisFirst Cardiology Clinic, School of Medicine, University of Athens, Athens, Greece.
Christodoulos StefanadisFirst Cardiology Clinic, School of Medicine, University of Athens, Athens, Greece.
Christos PitsavosFirst Cardiology Clinic, School of Medicine, University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this work was to evaluate the association between coffee consumption and 10-year cardiovascular disease (CVD) incidence in the ATTICA study, and whether this is modified by the presence or absence of metabolic syndrome (MetS) at baseline.

methodsDuring 2001-2002, 3042 healthy adults (1514 men and 1528 women) living in the greater area of Athens were voluntarily recruited to the ATTICA study. In 2011-2012, the 10-year follow-up was performed in 2583 participants (15% of the participants were lost to follow-up). Coffee consumption was assessed by a validated food-frequency questionnaire at baseline (abstention, low, moderate, heavy). Incidence of fatal or non-fatal CVD event was recorded using WHO-ICD-10 criteria and MetS was defined by the National Cholesterol Education Program Adult Treatment panel III (revised) criteria.

resultsOverall, after controlling for potential CVD risk factors, the multivariate analysis revealed a J-shaped association between daily coffee drinking and the risk for a first CVD event in a 10-year period. Particularly, the odds ratio for low (<150 ml/day), moderate (150-250 ml/day) and heavy coffee consumption (>250 ml/day), compared to abstention, were 0.44 (95% CI 0.29-0.68), 0.49 (95% CI 0.27-0.92) and 2.48 (95% CI 1.56-1.93), respectively. This inverse association was also verified among participants without MetS at baseline, but not among participants with the MetS.

conclusionsThese data support the protective effect of drinking moderate quantities of coffee (equivalent to approximately 1-2 cups daily) against CVD incidents. This protective effect was only significant for participants without MetS at baseline.

Indexed as

CoffeeDietAdultCardiovascular DiseasesFemaleGreeceHumansIncidenceMaleMiddle AgedProspective StudiesRisk FactorsCoffeeCardiovascular diseasesCoffeeInflammationMetabolic syndrome

Identifiers

PMID28424867

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.