Evidence map›Paper›PMID 28424785›Full record

ArticleBioMed research international2017

The Impact of Homocysteine, Vitamin B12, and Vitamin D Levels on Functional Outcome after First-Ever Ischaemic Stroke.

Merdin Markišić, Aleksandra M Pavlović, Dragan M Pavlović

Abstract read
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Plasma Cystine as a Marker of Acute Stroke Severity.Diagnostics (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Association of Vitamin B12 and Polymorphism ofNeuropsychiatric disease and treatment · 2024
    Article
  9. Association Between Serum Vitamin D Levels and Physical Outcomes of Patients Who Underwent Rehabilitation Following Ischemic Stroke.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. 25(OH) vitamin D and functional outcomes in older adults admitted to rehabilitation units: the safari study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Article
  18. The impact of homocysteine, BBMC infectious diseases · 2019
    Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Merdin MarkišićGeneral Hospital, Unit of Neurology, Svetog Save Street No. 33, Berane, Montenegro.
Aleksandra M PavlovićFaculty of Medicine, University of Belgrade, Neurology Clinic, Clinical Center of Serbia, Dr. Subotica Street No. 6, 11 000 Belgrade, Serbia.
Dragan M PavlovićFaculty for Special Education and Rehabilitation, University of Belgrade, Visokog Stevana Street No. 2, 11 000 Belgrade, Serbia.ORCID 0000-0001-6054-6572

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We explored the relationship between acute ischaemic stroke (IS) early functional outcome and serum levels of homocysteine, vitamin B12, and D in a noninterventional prospective clinical study. We enrolled 50 patients with first-ever IS and performed laboratory tests and functional assessment at three time points: on admission and three and six months after stroke. Modified Rankin Scale (mRS), NIHSS scale, and Barthel index (BI) scores were assessed in all participants by trained examiner blinded to laboratory data. Patients did not receive treatment that might alter laboratory data. Admission NIHSS correlated with homocysteine levels (

Indexed as

Recovery of FunctionAgedAged, 80 and overBrain IschemiaFemaleHomocysteineHumansMaleMiddle AgedStrokeVitamin B 12Vitamin DHomocysteineVitamin B 12Vitamin D

Identifiers

PMID28424785
PMCPMC5382296

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.