ArticleSensing and Bio-Sensing Research2017
Rapid, low cost prototyping of transdermal devices for personal healthcare monitoring.
Article in Sensing and Bio-Sensing Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 100 citations in OpenAlex.
- Wearable technologies in clinical trials for drug development: trends and emerging opportunities.Nature reviews. Drug discovery · 2026Review
- Barriers to translating continuous monitoring technologies for preventative medicine.Nature biomedical engineering · 2025Review
- Can we still use the Michaelis-Menten model for enzymatic microneedle sensors?Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Discriminating cocaine use from other sympathomimetics using wearable electrocardiographic (ECG) sensors.Drug and alcohol dependence · 2023Article
- Molecular Imprinted Polymers on Microneedle Arrays for Point of Care Transdermal Sampling and Sensing of Inflammatory Biomarkers.ACS omega · 2022Article
- A Comprehensive Review of the Recent Developments in Wearable Sweat-Sensing Devices.Sensors (Basel, Switzerland) · 2022Review
- Real-time continuous measurement of lactate through a minimally invasive microneedle patch: a phase I clinical study.BMJ innovations · 2022Article
- Wearable electrochemical biosensors to measure biomarkers with complex blood-to-sweat partition such as proteins and hormones.Mikrochimica acta · 2022Review
- Microfluidic chip connected to porous microneedle array for continuous ISF sampling.Drug delivery and translational research · 2022Article
- Bimetallic Nanomaterials-Based Electrochemical Biosensor Platforms for Clinical Applications.Micromachines · 2021Review
- Translation of Polymeric Microneedles for Treatment of Human Diseases: Recent Trends, Progress, and Challenges.Pharmaceutics · 2021Review
- Fabrication Methods for Microfluidic Devices: An Overview.Micromachines · 2021Review
- Towards wearable and implantable continuous drug monitoring: A review.Journal of pharmaceutical analysis · 2021Review
- Microneedles for transdermal diagnostics: Recent advances and new horizons.Biomaterials · 2020Review
- Nanoscale dynamic chemical, biological sensor material designs for control monitoring and early detection of advanced diseases.Materials today. Bio · 2020Review
- Connectivity of rapid-testing diagnostics and surveillance of infectious diseases.Bulletin of the World Health Organization · 2019Article
- Functionalized microneedles for continuous glucose monitoring.Nano convergence · 2018Review
- Delivering precision antimicrobial therapy through closed-loop control systems.The Journal of antimicrobial chemotherapy · 2018Review
- Innovation at the Intersection of Alcohol and HIV Research.AIDS and behavior · 2017Article
- Towards a minimally invasive device for beta-lactam monitoring in humans.Electrochemistry communications · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The next generation of devices for personal healthcare monitoring will comprise molecular sensors to monitor analytes of interest in the skin compartment. Transdermal devices based on microneedles offer an excellent opportunity to explore the dynamics of molecular markers in the interstitial fluid, however good acceptability of these next generation devices will require several technical problems associated with current commercially available wearable sensors to be overcome. These particularly include reliability, comfort and cost. An essential pre-requisite for transdermal molecular sensing devices is that they can be fabricated using scalable technologies which are cost effective. We present here a minimally invasive microneedle array as a continuous monitoring platform technology. Method for scalable fabrication of these structures is presented. The microneedle arrays were characterised mechanically and were shown to penetrate human skin under moderate thumb pressure. They were then functionalised and evaluated as glucose, lactate and theophylline biosensors. The results suggest that this technology can be employed in the measurement of metabolites, therapeutic drugs and biomarkers and could have an important role to play in the management of chronic diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.