Evidence map›Paper›PMID 28424696›Full record

ReviewFrontiers in immunology2017

Spirochetal Lipoproteins and Immune Evasion.

Alexei Christodoulides, Ani Boyadjian, Theodoros Kelesidis

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Screening of Surface-Exposed Lipoproteins ofFrontiers in microbiology · 2022
    Article
  4. Approaches to Understanding Mechanisms of Dentilisin Protease Complex Expression inFrontiers in cellular and infection microbiology · 2021
    Review
  5. Deciphering the Role ofFrontiers in immunology · 2021
    Article
  6. Review
  7. Article
  8. Interactions between Borrelia burgdorferi and ticks.Nature reviews. Microbiology · 2020
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alexei ChristodoulidesDavid Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA.
Ani BoyadjianDavid Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA.
Theodoros KelesidisDavid Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA.
University of California, Los Angeles · US

Funding

Oxidized HDL in the intersection of HIV, immune activation and atherosclerosisK08AI108272 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KELESIDIS, THEODOROS · 2013 to 2017
$915k
NIAID NIH HHS K08 AI108272
6 · The paper itself

Abstract

Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes. Lipoproteins are pro-inflammatory, modulatory of immune responses, and enable the spirochetes to evade the immune system. In this article, we review the modulatory effects of spirochetal lipoproteins related to immune evasion. Understanding lipoprotein-induced immunomodulation will aid in elucidating innate pathogenesis processes and subsequent adaptive mechanisms potentially relevant to spirochetal disease vaccine development and treatment.

Indexed as

evasion mechanismimmune systemimmunitylipoproteinsspirochetes

Identifiers

PMID28424696
PMCPMC5372817
OpenAlexW2601174950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.