Evidence map›Paper›PMID 28424620›Full record

ArticleFrontiers in pharmacology2017

Relations between Effects and Structure of Small Bicyclic Molecules on the Complex Model System

Matteo Brilli, Andrea Trabocchi, Tobias Weil, Duccio Cavalieri, Irene Stefanini

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Matteo BrilliCentre for Research and Innovation, Fondazione Edmund MachTrento, Italy.
Andrea TrabocchiDepartment of Chemistry "Ugo Schiff", University of FlorenceFlorence, Italy.
Tobias WeilCentre for Research and Innovation, Fondazione Edmund MachTrento, Italy.
Duccio CavalieriDepartment of Biology, University of FlorenceFlorence, Italy.
Irene StefaniniDivision of Biomedical Cell Biology, Warwick Medical School, University of WarwickCoventry, UK.
Fondazione Edmund Mach · ITUniversity of Florence · ITUniversity of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of compounds able to modify biological functions largely took advantage of parallel synthesis to generate a broad chemical variance of compounds to be tested for the desired effect(s). The budding yeast

Indexed as

drug developmentdrug screeninghigh-throughput screening (HTS)phenotypic screeningprincipal component analysisSaccharomyces cerevisiaesmall compoundsstepwise regression analysis

Identifiers

PMID28424620
PMCPMC5371657
OpenAlexW2597504722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.