Evidence map›Paper›PMID 28424616›Full record

ArticleFrontiers in pharmacology2017

Whole Blood Cytokine Response to Local Traffic-Related Particulate Matter in Peruvian Children With and Without Asthma.

Jesse P Negherbon, Karina Romero, D'Ann L Williams, Rafael E Guerrero-Preston, Thomas Hartung, Alan L Scott, Patrick N Breysse, William Checkley, Nadia N Hansel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Clinical and inflammatory features of traffic-related diesel exposure in children with asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jesse P NegherbonDepartment of Environmental Health Sciences, Bloomberg School of Public Health, The Johns Hopkins University, BaltimoreMD, USA.
Karina RomeroAsociación Benéfica PrismaLima, Perú.
D'Ann L WilliamsDepartment of Environmental Health Sciences, Bloomberg School of Public Health, The Johns Hopkins University, BaltimoreMD, USA.
Rafael E Guerrero-PrestonHead and Neck Cancer Research Division, Department of Otolaryngology, School of Medicine, The Johns Hopkins University, BaltimoreMD, USA.
Thomas HartungDepartment of Environmental Health Sciences, Bloomberg School of Public Health, The Johns Hopkins University, BaltimoreMD, USA.
Alan L ScottW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, The Johns Hopkins University, BaltimoreMD, USA.
Patrick N BreysseDepartment of Environmental Health Sciences, Bloomberg School of Public Health, The Johns Hopkins University, BaltimoreMD, USA.
William CheckleyAsociación Benéfica PrismaLima, Perú.
Nadia N HanselDepartment of Environmental Health Sciences, Bloomberg School of Public Health, The Johns Hopkins University, BaltimoreMD, USA.
Johns Hopkins University · USJohns Hopkins Medicine · USPrisma · PE

Funding

Genetic Susceptibility to Asthma and IndoorAir Pollution in PeruR01ES018845 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N · 2010 to 2014
$3.8M
NIEHS NIH HHS R01 ES018845
6 · The paper itself

Abstract

This study sought to investigate if acute phase immune responses of whole blood from Peruvian children with controlled and uncontrolled asthma differed from children without asthma, following exposure to traffic-related particulate matter (TRPM). TRPM, including particulate matter from diesel combustion, has been shown to stimulate acute airway inflammation in individuals with and without asthma. For this study, a whole blood assay (WBA) was used to test peripheral whole blood samples from 27 children with asthma, and 12 without asthma. Participant blood samples were stimulated,

Indexed as

asthmacytokinesinflammationparticulate matterwhole blood assay

Identifiers

PMID28424616
PMCPMC5371665
OpenAlexW2598743507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.