Evidence map›Paper›PMID 28424611›Full record

ArticleFrontiers in aging neuroscience2017

Modafinil-Induced Changes in Functional Connectivity in the Cortex and Cerebellum of Healthy Elderly Subjects.

Miriam Punzi, Tommaso Gili, Laura Petrosini, Carlo Caltagirone, Gianfranco Spalletta, Stefano L Sensi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Article
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  4. Drug Repurposing: A Network-based Approach to Amyotrophic Lateral Sclerosis.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Miriam PunziDepartment of Neurosciences, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-PescaraChieti, Italy.
Tommaso GiliMuseo Storico della Fisica e Centro Studi e Ricerche Enrico FermiRome, Italy.
Laura PetrosiniSanta Lucia FoundationRome, Italy.
Carlo CaltagironeSanta Lucia FoundationRome, Italy.
Gianfranco SpallettaSanta Lucia FoundationRome, Italy.
Stefano L SensiDepartment of Neurosciences, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-PescaraChieti, Italy.
University of Chieti-Pescara · ITEnrico Fermi Center for Study and Research · ITFondazione Santa Lucia · ITSapienza University of Rome · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past few years, cognitive enhancing drugs (CEDs) have gained growing interest and the focus of investigations aimed at exploring their use to potentiate the cognitive performances of healthy individuals. Most of this exploratory CED-related research has been performed on young adults. However, CEDs may also help to maintain optimal brain functioning or compensate for subtle and or subclinical deficits associated with brain aging or early-stage dementia. In this study, we assessed effects on resting state brain activity in a group of healthy elderly subjects undergoing acute administration of modafinil, a wakefulness-promoting agent. To that aim, participants (

Indexed as

agingcognitive enhancing drugsconnectivitydopamineeigenvector centralitygraph theoryresting state fMRI

Identifiers

PMID28424611
PMCPMC5371677
OpenAlexW2600296276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.