Evidence map›Paper›PMID 28424321›Full record

ArticleOpen biology2017

The

Hideyuki Shimizu, Marian B Wilkin, Simon A Woodcock, Alessandro Bonfini, Yvonne Hung, Sabine Mazaleyrat, Martin Baron

Open access · goldAbstract read
In one paragraph

Article in Open biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. The Memory Gene,Biomolecules · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Open biology · 2019
    Article
  13. Molecular control of the female germline stem cell niche size in Drosophila.Cellular and molecular life sciences : CMLS · 2019
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 3 countries.

Hideyuki ShimizuUniversity of Manchester, School of Biological Sciences, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Road, Manchester M13 9PL, UK.
Marian B WilkinUniversity of Manchester, School of Biological Sciences, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Road, Manchester M13 9PL, UK.
Simon A WoodcockUniversity of Manchester, School of Biological Sciences, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Road, Manchester M13 9PL, UK.
Alessandro BonfiniUniversity of Manchester, School of Biological Sciences, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Road, Manchester M13 9PL, UK.ORCID 0000-0001-6642-8665
Yvonne HungUniversity of Manchester, School of Biological Sciences, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Road, Manchester M13 9PL, UK.
Sabine MazaleyratUniversity of Manchester, School of Biological Sciences, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Road, Manchester M13 9PL, UK.
Martin BaronUniversity of Manchester, School of Biological Sciences, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Road, Manchester M13 9PL, UK mbaron@manchester.ac.uk.ORCID 0000-0002-7375-5784
Google (United States) · US

Funding

Biotechnology and Biological Sciences Research Council BB/H000976/1Biotechnology and Biological Sciences Research Council BB/P000215/1
6 · The paper itself

Abstract

The developmental signalling protein Notch can be proteolytically activated following ligand-interaction at the cell surface, or can be activated independently of its ligands, following Deltex (Dx)-induced Notch endocytosis and trafficking to the lysosomal membrane. The means by which different pools of Notch are directed towards these alternative outcomes remains poorly understood. We found that the

Indexed as

Stem Cell NicheDrosophila ProteinsGene ExpressionGerm CellsMembrane ProteinsMutationProtein TransportReceptors, NotchSignal TransductionTight Junction ProteinsDrosophila ProteinsDX protein, DrosophilaMembrane Proteinspyd protein, DrosophilaReceptors, NotchTight Junction ProteinsDrosophilaendocytosisNotchsignallingZO-1

Identifiers

PMID28424321
PMCPMC5413905
OpenAlexW2607029750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.