Evidence map›Paper›PMID 28424283›Full record

ArticleJournal of virology2017

Simian Immunodeficiency Virus Targeting of CXCR3

Masayuki Fujino, Hirotaka Sato, Tomotaka Okamura, Akihiko Uda, Satoshi Takeda, Nursarat Ahmed, Shigeyuki Shichino, Teiichiro Shiino, Yohei Saito, Satoru Watanabe and 10 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 2 countries.

Masayuki FujinoAIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Hirotaka SatoAIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Tomotaka OkamuraTsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition, Tsukuba, Ibaraki, Japan.
Akihiko UdaDepartment of Veterinary Science, National Institute of Infectious Diseases, Tokyo, Japan.
Satoshi TakedaAIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Nursarat AhmedAIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Shigeyuki ShichinoDepartment of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Teiichiro ShiinoInfectious Diseases Surveillance Center, National Institute of Infectious Diseases, Tokyo, Japan.
Yohei SaitoAIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Satoru WatanabeAIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Chie SugimotoDivision of Immunology, Tulane National Primate Research Center, Tulane University, Covington, Louisiana, USA.
Marcelo J KurodaDivision of Immunology, Tulane National Primate Research Center, Tulane University, Covington, Louisiana, USA.
Manabu AtoDepartment of Immunology, National Institute of Infectious Diseases, Tokyo, Japan.
Yoshiyuki NagaiCenter of Research Network for Infectious Diseases, Riken, Tokyo, Japan.
Shuji IzumoMolecular Pathology, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Kouji MatsushimaDepartment of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Masaaki MiyazawaDepartment of Immunology, Kindai University School of Medicine, Osaka-Sayama, Osaka, Japan.
Aftab A AnsariDepartment of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA.
Francois VillingerDepartment of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA.
Kazuyasu MoriAIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan mori@nih.go.jp.ORCID http://orcid.org/0000-0002-1841-6376
National Institute of Infectious Diseases · JPEmory University · USThe University of Tokyo · JPTulane University · USKagoshima University · JPKindai University · JPNational Institute of Biomedical Innovation, Health and Nutrition · JP

Funding

Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
Macrophages in the pathogenesis of AIDSR01AI097059 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KURODA, MARCELO J · 2012 to 2016
$4.0M
Role of Macrophages in Lung Disease Pathogenesis of Pediatric AIDSR01HL125054 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI KURODA, MARCELO J, VEAZEY, RONALD S. · 2014 to 2017
$3.3M
Targeting HIV Lung Reservoir in the Macaque ModelR33AI110163 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KURODA, MARCELO J · 2016 to 2018
$1.5M
Effects of Opioids on SIV Reservoirs in Brain Macrophages of Rhesus MacaquesR21DA041017 · NIDA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KURODA, MARCELO J · 2015 to 2017
$1.1M
Targeting HIV Lung Reservoir in the Macaque ModelR21AI110163 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KURODA, MARCELO J · 2014 to 2015
$457k
NHLBI NIH HHS R01 HL125054NIAID NIH HHS R01 AI097059NIAID NIH HHS R21 AI110163NIAID NIH HHS R33 AI110163NIDA NIH HHS R21 DA041017NIH HHS P51 OD011104
6 · The paper itself

Abstract

Glycosylation of Env defines pathogenic properties of simian immunodeficiency virus (SIV). We previously demonstrated that pathogenic SIVmac239 and a live-attenuated, quintuple deglycosylated Env mutant (Δ5G) virus target CD4

Indexed as

AnimalsCD4-Positive T-LymphocytesChemokine CXCL10Gene ExpressionGene Expression ProfilingImmunity, InnateMacaca mulattaMacrophagesMaleMonocytesReceptors, CXCR3Simian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusT-Lymphocyte SubsetsChemokine CXCL10Receptors, CXCR3CD4+ T cellCXCL10CXCR3glycosylationinnate immunitymacrophagesmonocytespathogenesisSIVTh1

Identifiers

PMID28424283
PMCPMC5469254
OpenAlexW2606725356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.