ArticleThe Journal of experimental medicine2017
Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2.
Open access · bronzeAbstract read
In one paragraph
Article in The Journal of experimental medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 1 pooled it
9.5field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
89 citing papers in PubMed, 1 synthesis or guideline pooled it, 170 citations in OpenAlex.
- Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma.Scientific reports · 2021Pooled it
- Integrated clinical and genomic evaluation of guadecitabine (SGI-110) in peripheral T-cell lymphoma.Leukemia · 2022Trial
- Primary central nervous system T cell lymphoma involving multiple brain and spinal cord lesions with SETD2 mutation.International journal of hematology · 2026Article
- Divergent molecular pathways drive monomorphic epitheliotropic and enteropathy-associated intestinal T-cell lymphoma.Leukemia · 2026Article
- Case Report: Targeting the Achilles' heel of monomorphic epitheliotropic intestinal T-cell lymphoma.Frontiers in oncology · 2026Article
- Immunophenotyping and Mutation Analysis of Canine Intestinal T-Cell Lymphoma: A Comparative Pathological Study of Human Enteropathy-Associated T-Cell Lymphoma.Veterinary and comparative oncology · 2025Article
- Emerging role of SETD2 in the development and function of immune cells.Genes & diseases · 2025Review
- Epidemiology of mature T-cell and NK-cell neoplasms: east and west.The Lancet regional health. Western Pacific · 2025Review
- ATF7IP/SETDB1-mediated epigenetic programming regulates thymic homing and T lymphopoiesis of hematopoietic progenitors during embryogenesis.Nature communications · 2025Article
- Malignancies in Celiac Disease-A Hidden Threat with Diagnostic Pitfalls.Biomedicines · 2025Review
- Hepatosplenic T-cell lymphoma in children and adolescents.Blood advances · 2025Review
- Butyrate-producingGut · 2025Article
- Clinical and pathological analysis of indolent T-cell lymphoproliferative disease of the gastrointestinal tract.Frontiers in immunology · 2025Article
- Comprehensive investigation of gene mutations in canine large cell gastrointestinal lymphoma.Frontiers in veterinary science · 2025Article
- A practical approach to the modern diagnosis and classification of T- and NK-cell lymphomas.Blood · 2024Review
- Catalytic activity of Setd2 is essential for embryonic development in mice: establishment of a mouse model harboring patient-derived Setd2 mutation.Frontiers of medicine · 2024Article
- Monomorphic epitheliotropic intestinal T-cell lymphoma: report of four cases and literature review.The Journal of international medical research · 2024Review
- Clinicopathological and molecular genetic alterations in monomorphic-epitheliotropic intestinal T-cell lymphoma of the small intestine.European journal of medical research · 2024Article
- Single nucleotide polymorphism profiles of canine T-cell and null-cell lymphomas.Frontiers in veterinary science · 2024Article
- Updates in the Classification of T-cell Lymphomas and Lymphoproliferative Disorders.Current hematologic malignancy reports · 2023Review
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
36 authors at 14 institutions in 6 countries.
Andrea B MoffittDuke Center for Genomics and Computational Biology, Duke University, Durham, NC 27708.ORCID 0000-0001-5964-7851
Sarah L OndrejkaPathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH 44195.ORCID 0000-0001-9431-2889
Matthew McKinneyDuke Cancer Institute, Duke University School of Medicine, Durham, NC 27710.ORCID 0000-0002-2979-4882
Rachel E RempelDuke Cancer Institute, Duke University School of Medicine, Durham, NC 27710.ORCID 0000-0002-6113-1659
John R GoodladHaematological Malignancy Diagnostic Service, St. James's University Hospital, Leeds LS9 7TF, England, UK.
Chun Huat TehHaematology Department, Western General Hospital, Edinburgh EH14 1TY, Scotland, UK.
Sirpa LeppaDepartment of Oncology and Research Program Unit, Faculty of Medicine, Helsinki University Hospital Cancer Center and University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0002-8265-511X
Susanna MannistoDepartment of Oncology and Research Program Unit, Faculty of Medicine, Helsinki University Hospital Cancer Center and University of Helsinki, 00014 Helsinki, Finland.
Panu E KovanenHUSLAB and Medicum, Helsinki University Hospital Cancer Center and University of Helsinki, 00014 Helsinki, Finland.
Eric TseUniversity of Hong Kong, Queen Mary Hospital, Hong Kong, China.ORCID 0000-0002-8351-4722
Rex K H Au-YeungUniversity of Hong Kong, Queen Mary Hospital, Hong Kong, China.
Yok-Lam KwongUniversity of Hong Kong, Queen Mary Hospital, Hong Kong, China.
Gopesh SrivastavaUniversity of Hong Kong, Queen Mary Hospital, Hong Kong, China.
Javeed IqbalUniversity of Nebraska Medical Center, Omaha, NE 68198.ORCID 0000-0003-3668-0629
Jiayu YuUniversity of Nebraska Medical Center, Omaha, NE 68198.
Kikkeri NareshImperial College London, London SW7 2AZ, England, UK.
Diego VillaBritish Columbia Cancer Agency, University of British Columbia, Vancouver, BC V6R 1ZE, Canada.ORCID 0000-0002-4625-3009
Randy D GascoyneBritish Columbia Cancer Agency, University of British Columbia, Vancouver, BC V6R 1ZE, Canada.ORCID 0000-0002-2610-5690
Jonathan SaidUniversity of California, Los Angeles, Los Angeles, CA 90095.ORCID 0000-0001-9474-2563
Magdalena B CzaderIndiana University, Indianapolis, IN 46202.
Amy ChadburnPresbyterian Hospital, Pathology and Cell Biology, Cornell University, New York, NY 10065.
Kristy L RichardsUniversity of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0001-5765-6631
Deepthi RajagopalanDuke Cancer Institute, Duke University School of Medicine, Durham, NC 27710.
Nicholas S DavisDuke Cancer Institute, Duke University School of Medicine, Durham, NC 27710.
Eileen C SmithDuke Cancer Institute, Duke University School of Medicine, Durham, NC 27710.ORCID 0000-0002-2116-8094
Brooke C PalusDuke Cancer Institute, Duke University School of Medicine, Durham, NC 27710.
Tiffany J TzengDuke Cancer Institute, Duke University School of Medicine, Durham, NC 27710.
Jane A HealyDuke Cancer Institute, Duke University School of Medicine, Durham, NC 27710.
Patricia L LugarDepartment of Medicine, Duke University School of Medicine, Durham, NC 27710.
Jyotishka DattaDepartment of Statistical Science, Duke University, Durham, NC 27708.ORCID 0000-0001-5991-5182
Cassandra LoveDuke Cancer Institute, Duke University School of Medicine, Durham, NC 27710.
Shawn LevyHudson Alpha Institute for Biotechnology, Huntsville, AL 35806.
David B DunsonDepartment of Statistical Science, Duke University, Durham, NC 27708.
Yuan ZhuangDepartment of Immunology, Duke University School of Medicine, Durham, NC 27710.
Eric D HsiPathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH 44195.
Sandeep S DaveDuke Center for Genomics and Computational Biology, Duke University, Durham, NC 27708.ORCID 0000-0003-4848-9768
Duke University · USQueen Mary Hospital · CNUniversity of Helsinki · FIBC Cancer Agency · CACleveland Clinic · USUniversity of Nebraska Medical Center · USCornell University · USHudsonAlpha Institute for Biotechnology · USImperial College London · GBIndiana University – Purdue University Indianapolis · USSt James's University Hospital · GBUniversity of California, Los Angeles · USUniversity of North Carolina at Chapel Hill · USWestern General Hospital · GB
Funding
Genetics Training Grant-Year 26T32GM007754 · NIGMS · DUKE UNIVERSITY · PI HAASE, STEVEN B · 1985 to 2019
$8.3MAbstract
Enteropathy-associated T cell lymphoma (EATL) is a lethal, and the most common, neoplastic complication of celiac disease. Here, we defined the genetic landscape of EATL through whole-exome sequencing of 69 EATL tumors.
Indexed as
AnimalsDNA Copy Number VariationsEnteropathy-Associated T-Cell LymphomaFemaleGene Expression ProfilingGene SilencingHistone-Lysine N-MethyltransferaseHumansMaleMice, KnockoutMiddle AgedMutationSequence Analysis, DNAT-LymphocytesHistone-Lysine N-MethyltransferaseSETD2 protein, human
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.