Evidence map›Paper›PMID 28424238›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

IL-20 Signaling in Activated Human Neutrophils Inhibits Neutrophil Migration and Function.

Portia Gough, Sundar Ganesan, Sandip K Datta

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02262819 (Human Immunity Against Staphylococcus Aureus Skin Infection), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02262819 phase1completednot on this map

Human Immunity Against Staphylococcus Aureus Skin Infection

TypeinterventionalSponsorNational Institute of Allergy and Infectious Diseases (NIAID)Ran2014 to 2019Enrolled49ConditionsStaphylococcus Aureus Skin InfectionArmsS. aureus
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. IL-26 in the Lung and Its Role in COPD Inflammation.Journal of personalized medicine · 2022
    Review
  7. Exploring the Role ofToxins · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Portia GoughBacterial Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and.
Sundar GanesanBiological Imaging Section, Research Technology Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0003-1132-2016
Sandip K DattaBacterial Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and dattas@niaid.nih.gov.ORCID 0000-0003-0243-7815
National Institutes of Health · US

Funding

Infectious Diseases Research Technologies Core - BethesdaZICAI001051 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CHERRY, JAMES · 2009 to 2025
$226.1M
Host Immunity Against BacteriaZIAAI001043 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MYLES, IAN · 2009 to 2025
$18.9M
Intramural NIH HHS ZIA AI001043
6 · The paper itself

Abstract

Neutrophils possess multiple antimicrobial mechanisms that are critical for protection of the host against infection with extracellular microbes, such as the bacterial pathogen

Indexed as

Neutrophil ActivationSignal TransductionBronchiCell Migration Assays, LeukocyteCell MovementCytokinesEpithelial CellsExocytosisHumansInterleukinsNeutrophilsPhagocytosisReceptors, InterleukinStaphylococcus aureusCytokinesinterleukin 20interleukin-20 receptorInterleukinsReceptors, Interleukin

Identifiers

PMID28424238
PMCPMC5476316
OpenAlexW2618625634

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.