Evidence map›Paper›PMID 28424160›Full record

ArticleDiabetes2017

Heterogeneous Nuclear Ribonucleoprotein F Stimulates Sirtuin-1 Gene Expression and Attenuates Nephropathy Progression in Diabetic Mice.

Chao-Sheng Lo, Yixuan Shi, Isabelle Chenier, Anindya Ghosh, Chin-Han Wu, Jean-Francois Cailhier, Jean Ethier, Jean-Baptiste Lattouf, Janos G Filep, Julie R Ingelfinger and 2 more

Abstract read
In one paragraph

Article in Diabetes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Post‑translational modifications in diabetic kidney disease (Review).International journal of molecular medicine · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The sirtuin family in health and disease.Signal transduction and targeted therapy · 2022
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Role of sirtuin-1 in diabetic nephropathy.Journal of molecular medicine (Berlin, Germany) · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chao-Sheng LoCentre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) and Département de médecine, Université de Montréal, Montreal, QC, Canada.
Yixuan ShiCentre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) and Département de médecine, Université de Montréal, Montreal, QC, Canada.
Isabelle ChenierCentre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) and Département de médecine, Université de Montréal, Montreal, QC, Canada.
Anindya GhoshCentre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) and Département de médecine, Université de Montréal, Montreal, QC, Canada.
Chin-Han WuCentre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) and Département de médecine, Université de Montréal, Montreal, QC, Canada.
Jean-Francois CailhierCentre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) and Département de médecine, Université de Montréal, Montreal, QC, Canada.
Jean EthierCentre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) and Département de médecine, Université de Montréal, Montreal, QC, Canada.
Jean-Baptiste LattoufCentre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) and Département de médecine, Université de Montréal, Montreal, QC, Canada.
Janos G FilepCentre de recherche, Hôpital Maisonneuve-Rosemont and Department of Pathology and Cell Biology, Université de Montréal, Montreal, QC, Canada.
Julie R IngelfingerPediatric Nephrology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Shao-Ling ZhangCentre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) and Département de médecine, Université de Montréal, Montreal, QC, Canada john.chan@umontreal.ca shao.ling.zhang@umontreal.ca.
John S D ChanCentre de recherche, Centre hospitalier de l'Université de Montréal (CRCHUM) and Département de médecine, Université de Montréal, Montreal, QC, Canada john.chan@umontreal.ca shao.ling.zhang@umontreal.ca.

Funding

CIHR MOP-106688CIHR MOP-84363CIHR MOP-86450CIHR MOP-93650CIHR MOP-97742
6 · The paper itself

Abstract

We investigated the mechanism of heterogeneous nuclear ribonucleoprotein F (hnRNP F) renoprotective action in a type 2 diabetes (T2D) mouse model (

Indexed as

AcetylationAgedAnimalsApoptosisBlotting, WesternCase-Control StudiesCells, CulturedDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Diabetic NephropathiesDisease Models, AnimalDisease ProgressionFemaleFibrosisForkhead Box Protein O3Gene Expression RegulationForkhead Box Protein O3FOXO3 protein, humanFoxO3 protein, mouseFOXO3 protein, ratHeterogeneous-Nuclear Ribonucleoprotein Group F-Hleptin receptor, mouseReceptors, LeptinSIRT1 protein, humanSirt1 protein, mouseSirt1 protein, ratSirtuin 1Tumor Suppressor Protein p53

Identifiers

PMID28424160
PMCPMC5482081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.