ArticleCell reports2017
Diversity in Excitation-Inhibition Mismatch Underlies Local Functional Heterogeneity in the Rat Auditory Cortex.
Article in Cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Decoding auditory cognition: Unraveling the corticostriatal-SNr circuit's role in frequency discrimination accuracy.iScience · 2025Article
- Article
- Corticostriatal Neurons in the Anterior Auditory Field Regulate Frequency Discrimination Behavior.Neuroscience bulletin · 2023Article
- Perinatal Opioid Exposure Results in Persistent Hypoconnectivity of Excitatory Circuits and Reduced Activity Correlations in Mouse Primary Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Sparse Coding in Temporal Association Cortex Improves Complex Sound Discriminability.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- In Vivo Whole-Cell Patch-Clamp Methods: Recent Technical Progress and Future Perspectives.Sensors (Basel, Switzerland) · 2021Review
- Article
- Differential Inhibitory Configurations Segregate Frequency Selectivity in the Mouse Inferior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Local homogeneity of tonotopic organization in the primary auditory cortex of marmosets.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Anterior Auditory Field Is Needed for Sound Categorization in Fear Conditioning Task of Adult Rat.Frontiers in neuroscience · 2019Article
- Article
- Direct Relay Pathways from Lemniscal Auditory Thalamus to Secondary Auditory Field in Mice.Cerebral cortex (New York, N.Y. : 1991) · 2018Article
- A Non-canonical Reticular-Limbic Central Auditory Pathway via Medial Septum Contributes to Fear Conditioning.Neuron · 2018Article
- Sublaminar Subdivision of Mouse Auditory Cortex Layer 2/3 Based on Functional Translaminar Connections.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Cortical neurons are heterogeneous in their functional properties. This heterogeneity is fundamental for the processing of different features of sensory information. However, functional diversity within a local group of neurons is poorly understood. Here, we demonstrate that neighboring cortical neurons in layer 5 but not those of layer 4 of the rat anterior auditory field (AAF) exhibited a surprisingly high level of diversity in tonal receptive fields. In vivo whole-cell voltage-clamp recordings revealed that the diversity of frequency representation was due to a spectral mismatch between synaptic excitation and inhibition to varying degrees. The spectral distribution of excitation was skewed at different levels, whereas inhibition was homogeneous and non-skewed, similar to the summed spiking activity of local neuronal ensembles, which further enhanced diversity. Our results indicate that AAF in the auditory cortex is involved in processing auditory information in a highly refined manner that is important for complex pattern recognition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.