Evidence map›Paper›PMID 28422985›Full record

ArticlePloS one2017

Revising mtDNA haplotypes of the ancient Hungarian conquerors with next generation sequencing.

Endre Neparáczki, Klaudia Kocsy, Gábor Endre Tóth, Zoltán Maróti, Tibor Kalmár, Péter Bihari, István Nagy, György Pálfi, Erika Molnár, István Raskó and 1 more

Abstract readHistorical Article
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  20. A genetic perspective on Longobard-Era migrations.European journal of human genetics : EJHG · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Endre NeparáczkiDepartment of Genetics, University of Szeged, Szeged, Hungary.
Klaudia KocsyDepartment of Genetics, University of Szeged, Szeged, Hungary.
Gábor Endre TóthDepartment of Genetics, University of Szeged, Szeged, Hungary.
Zoltán MarótiDepartment of Pediatrics and Pediatric Health Center, University of Szeged, Faculty of Medicine, Szeged, Hungary.
Tibor KalmárDepartment of Pediatrics and Pediatric Health Center, University of Szeged, Faculty of Medicine, Szeged, Hungary.
Péter BihariSeqOmics Biotechnology Ltd., Mórahalom, Hungary.
István NagySeqOmics Biotechnology Ltd., Mórahalom, Hungary.
György PálfiDepartment of Biological Anthropology University of Szeged, Szeged, Hungary.
Erika MolnárDepartment of Biological Anthropology University of Szeged, Szeged, Hungary.
István RaskóInstitute of Genetics, Biological Research Centre, Szeged, Hungary.
Tibor TörökDepartment of Genetics, University of Szeged, Szeged, Hungary.ORCID http://orcid.org/0000-0002-2128-1126

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As part of the effort to create a high resolution representative sequence database of the medieval Hungarian conquerors we have resequenced the entire mtDNA genome of 24 published ancient samples with Next Generation Sequencing, whose haplotypes had been previously determined with traditional PCR based methods. We show that PCR based methods are prone to erroneous haplotype or haplogroup determination due to ambiguous sequence reads, and many of the resequenced samples had been classified inaccurately. The SNaPshot method applied with published ancient DNA authenticity criteria is the most straightforward and cheapest PCR based approach for testing a large number of coding region SNP-s, which greatly facilitates correct haplogroup determination.

Indexed as

HaplotypesPaleontologyBone and BonesDNA, AncientDNA, MitochondrialFossilsHigh-Throughput Nucleotide SequencingHistory, MedievalHumansHungaryMolecular TypingPolymerase Chain ReactionPolymorphism, Single NucleotideSequence Analysis, DNADNA, AncientDNA, Mitochondrial

Identifiers

PMID28422985
PMCPMC5396865

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.