ArticleScientific reports2017
Heritability maps of human face morphology through large-scale automated three-dimensional phenotyping.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Advancement in Human Face Prediction Using DNA.Genes · 2023Pooled it
- Positional programs in early murine facial development and their role in human facial shape variability.Nature communications · 2025Article
- Exploring the association between SNPs and facial morphology in a Spanish population.Scientific reports · 2025Article
- Optimized phenotyping of complex morphological traits: enhancing discovery of common and rare genetic variants.Briefings in bioinformatics · 2025Article
- The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling.Nature communications · 2024Article
- De Novo Dissecting the Three-Dimensional Facial Morphology of 2379 Han Chinese Individuals.Phenomics (Cham, Switzerland) · 2024Article
- Article
- Review
- The Facial Characteristics of Individuals with Posterior Crossbite: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2023Article
- The heritability of vocal tract structures estimated from structural MRI in a large cohort of Dutch twins.Human genetics · 2022Article
- Gattaca as a lens on contemporary genetics: marking 25 years into the film's "not-too-distant" future.Genetics · 2022Article
- Influence of the nutritional status on facial morphology in young Japanese women.Scientific reports · 2022Article
- Craniofacial superimposition: a review of focus distance estimation methods and an extension to profile view photographs.International journal of legal medicine · 2022Review
- Genetic influences on dentognathic morphology in the Jirel population of Nepal.Anatomical record (Hoboken, N.J. : 2007) · 2022Article
- Decoding the Human Face: Progress and Challenges in Understanding the Genetics of Craniofacial Morphology.Annual review of genomics and human genetics · 2022Review
- Review
- Article
- Valproic acid-induced changes of 4D nuclear morphology in astrocyte cells.Molecular biology of the cell · 2021Article
- Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations.PLoS genetics · 2021Article
- 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies.PLoS genetics · 2021Article
Corrections and comments
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Authors and funding
4 authors.
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Abstract
The human face is a complex trait under strong genetic control, as evidenced by the striking visual similarity between twins. Nevertheless, heritability estimates of facial traits have often been surprisingly low or difficult to replicate. Furthermore, the construction of facial phenotypes that correspond to naturally perceived facial features remains largely a mystery. We present here a large-scale heritability study of face geometry that aims to address these issues. High-resolution, three-dimensional facial models have been acquired on a cohort of 952 twins recruited from the TwinsUK registry, and processed through a novel landmarking workflow, GESSA (Geodesic Ensemble Surface Sampling Algorithm). The algorithm places thousands of landmarks throughout the facial surface and automatically establishes point-wise correspondence across faces. These landmarks enabled us to intuitively characterize facial geometry at a fine level of detail through curvature measurements, yielding accurate heritability maps of the human face (www.heritabilitymaps.info).
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