Evidence map›Paper›PMID 28422073›Full record

ReviewInternational journal of molecular sciences2017

Chemopreventive Strategies for Inflammation-Related Carcinogenesis: Current Status and Future Direction.

Yusuke Kanda, Mitsuhiko Osaki, Futoshi Okada

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Anti-inflammatory effect ofJournal of animal science and technology · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Beneficial Role ofBiology · 2021
    Review
  10. Article
  11. Article
  12. Review
  13. Fascin protein stabilization by miR-146a implicated in the process of a chronic inflammation-related colon carcinogenesis model.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2018
    Article
  14. World journal of gastroenterology · 2018
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yusuke KandaDivision of Pathological Biochemistry, Tottori University Faculty of Medicine, Yonago, Tottori 683-8503, Japan. kanda@med.tottori-u.ac.jp.
Mitsuhiko OsakiDivision of Pathological Biochemistry, Tottori University Faculty of Medicine, Yonago, Tottori 683-8503, Japan. osamitsu@med.tottori-u.ac.jp.
Futoshi OkadaDivision of Pathological Biochemistry, Tottori University Faculty of Medicine, Yonago, Tottori 683-8503, Japan. fuokada@med.tottori-u.ac.jp.
Tottori University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A sustained and chronically-inflamed environment is characterized by the presence of heterogeneous inflammatory cellular components, including neutrophils, macrophages, lymphocytes and fibroblasts. These infiltrated cells produce growth stimulating mediators (inflammatory cytokines and growth factors), chemotactic factors (chemokines) and genotoxic substances (reactive oxygen species and nitrogen oxide) and induce DNA damage and methylation. Therefore, chronic inflammation serves as an intrinsic niche for carcinogenesis and tumor progression. In this article, we summarize the up-to-date findings regarding definitive/possible causes and mechanisms of inflammation-related carcinogenesis derived from experimental and clinical studies. We also propose 10 strategies, as well as candidate agents for the prevention of inflammation-related carcinogenesis.

Indexed as

ChemopreventionAnimalsCarcinogenesisChronic DiseaseCytokinesDisease Models, AnimalDNA DamageHumansInflammationInflammation MediatorsNeoplasmsReactive Nitrogen SpeciesReactive Oxygen SpeciesCytokinesInflammation MediatorsReactive Nitrogen SpeciesReactive Oxygen Specieschemopreventionchronic inflammationinflammation-related carcinogenesis

Identifiers

PMID28422073
PMCPMC5412448
OpenAlexW2605496548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.