Evidence map›Paper›PMID 28421851›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2018

Global and multi-focal changes in cerebral blood flow during subthalamic nucleus stimulation in Parkinson's disease.

Asim M Mubeen, Babak Ardekani, Michele Tagliati, Ron Alterman, Vijay Dhawan, David Eidelberg, John J Sidtis

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Subthalamic Deep Brain Stimulation Affects Plasma Corticosterone Concentration and Peripheral Immunity Changes in Rat Model of Parkinson's Disease.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Asim M Mubeen1 Brain and Behavior Laboratory, The Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Babak Ardekani2 Center for Brain Imaging and Neuromodulation, The Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Michele Tagliati3 Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Ron Alterman4 Division of Neurosurgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Vijay Dhawan5 Feinstein Center for Neurosciences, NY, USA.
David Eidelberg5 Feinstein Center for Neurosciences, NY, USA.
John J Sidtis1 Brain and Behavior Laboratory, The Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Nathan Kline Institute for Psychiatric Research · USBeth Israel Deaconess Medical Center · USCedars-Sinai Medical Center · USCenter for Neurosciences · USFeinstein Institute for Medical Research · US

Funding

CORTICAL-SUBCORTICAL INTERACTION IN PD AND NORMAL SPEECHR01DC007658 · NIDCD · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI SIDTIS, DIANA L, SIDTIS, JOHN J · 2006 to 2016
$4.3M
NIDCD NIH HHS R01 DC007658
6 · The paper itself

Abstract

Electrical stimulation of subthalamic nuclei (STN) is a widely used therapy in Parkinson's disease (PD). While deep brain stimulation (DBS) of the STN alters the neurophysiological activity in basal ganglia, the therapeutic mechanism has not been established. A positron emission tomography (PET) study of cerebral blood flow (CBF) during speech production in PD subjects treated with STN-DBS found significant increases in global (whole-brain) CBF.

Indexed as

Deep Brain StimulationSubthalamic NucleusAgedAlgorithmsCerebrovascular CirculationFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedParkinson DiseasePositron-Emission TomographyPrincipal Component Analysiscerebral blood flowDeep brain stimulationParkinson’s diseasepositron emission tomographysubthalamic nucleus

Identifiers

PMID28421851
PMCPMC5888853
OpenAlexW2607390862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.