ArticleCancer research and treatment2018
Second Primary Cancer Risk among Kidney Cancer Patients in Korea: A Population-Based Cohort Study.
Article in Cancer research and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Risk of developing a second primary cancer following a renal cell carcinoma: a systematic review and meta-analysis.International urology and nephrology · 2026Pooled it
- Risk of developing subsequent primary breast cancer among non-breast cancer survivors: a retrospective cohort study.Breast cancer (Tokyo, Japan) · 2026Article
- Next-generation sequencing identifies the mutational signature of double primary and metastatic malignancies: A case report.Current urology · 2025Article
- Risk-based screening and prognostic analysis for second primary malignancies in kidney cancer patients: a retrospective cohort study based on large-scale population and Mendelian randomization analysis.International journal of medical sciences · 2025Article
- Renal cell carcinoma and risk of second primary cancer: A Danish nationwide cohort study.Cancer medicine · 2024Article
- Chance, ignorance, and the paradoxes of cancer: Richard Peto on developing preventative strategies under uncertainty.European journal of epidemiology · 2023Article
- [Treatment and prognosis of multiple primary malignant neoplasms complicated with renal cell carcinoma].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2022Article
- Effect of prior thyroid cancer on survival of primary liver cancer: a study based on the SEER database.Scientific reports · 2022Article
- Better Prognosis and Survival in Esophageal Cancer Survivors After Comorbid Second Primary Malignancies: A SEER Database-Based Study.Frontiers in surgery · 2022Article
- Prognosis of patients with axillary lymph node metastases from occult breast cancer: analysis of multicenter data.Radiation oncology journal · 2021Article
- Deciphering the Risk of Developing Second Primary Thyroid Cancer Following a Primary Malignancy-Who Is at the Greatest Risk?Cancers · 2021Article
- Second Primary Cancers After Kidney Cancers, and Kidney Cancers as Second Primary Cancers.European urology open science · 2021Article
- miR-34a in extracellular vesicles from bone marrow mesenchymal stem cells reduces rheumatoid arthritis inflammation via the cyclin I/ATM/ATR/p53 axis.Journal of cellular and molecular medicine · 2021Article
- Clear Cell Papillary Renal Cell Carcinoma Shares Distinct Molecular Characteristics and may be Significantly Associated With Higher Risk of Developing Second Primary Malignancy.Pathology oncology research : POR · 2021Article
- Post-Modern Epidemiology: When Methods Meet Matter.American journal of epidemiology · 2019Article
- Risk of second primary Cancer among bladder Cancer patients: a population-based cohort study in Korea.BMC cancer · 2018Article
- Primary prostate cancer synchronous with renal cell carcinoma: clinical experience and literature review.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieReview
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSecondary primary cancers (SPCs) commonly arise in patients with renal cell carcinoma (RCC). We designed the present study to estimate the SPC incidence in Korean patients with RCC. MATERIALS AND
methodsThe study cohort was population-based and consisted of 40,347 individuals from the Korean Central Cancer Registry who were diagnosed with primary renal cancer between 1993 and 2013. Standardized incidence ratios (SIRs) for SPCs were estimated for different ages at diagnosis, latencies, diagnostic periods, and treatments.
resultsFor patients with primary RCC, the risk of developing a SPC was higher than the risk of developing cancer in the general population (SIR, 1.13; 95% confidence interval, 1.08 to 1.18). Most cancer types showed higher incidences in patients with RCC than in the general population. However, the relative incidence of gastric cancer as an SPC varied by age. Gastric cancer incidence was elevated in young patients (< 30 years) with RCC, but reduced in older (≥ 30) patients with RCC. Patients with advanced RCC died prematurely, regardless of SPC development. In contrast, those with early-stage RCC survived for longer periods, although SPC development affected their post-RCC survival. After SPC development, women had better survival than men.
conclusionIn Korean patients with primary RCC, the incidence of SPC was 13% higher than the incidence of cancer in the general population. These findings may play important roles in the conduct of follow-up evaluations and education for patients with RCC.
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