Evidence map›Paper›PMID 28421542›Full record

ArticleMolecular neurobiology2018

Neural Stem Cell Transplantation Promotes Functional Recovery from Traumatic Brain Injury via Brain Derived Neurotrophic Factor-Mediated Neuroplasticity.

Liu-Lin Xiong, Yue Hu, Piao Zhang, Zhuo Zhang, Li-Hong Li, Guo-Dong Gao, Xin-Fu Zhou, Ting-Hua Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 80 citations in OpenAlex.

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  13. mNSCs overexpressingiScience · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Liu-Lin XiongInstitute of Neurological Disease, and Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Yue HuInstitute of Neurological Disease, and Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Piao ZhangInstitute of Neuroscience, and Animal Zoology Department, Kunming Medical University, Kunming, 650500, China.
Zhuo ZhangDepartment of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xian, 710032, China.
Li-Hong LiDepartment of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xian, 710032, China.
Guo-Dong GaoDepartment of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xian, 710032, China.
Xin-Fu ZhouDepartment of Human Physiology, Flinders University, GPO Box 2100, Adelaide, SA, 5001, Australia.
Ting-Hua WangInstitute of Neurological Disease, and Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, 610041, China. tinghua_neuron@263.net.
Air Force Medical University · CNKunming Medical University · CNWest China Hospital of Sichuan University · CNFlinders University · AU

Funding

National Key Technology Research and Development Program of the Ministry of Science and Technology of China No. 2014BAI01B10
6 · The paper itself

Abstract

Traumatic brain injury (TBI) induces cognitive impairments, motor and behavioral deficits. Previous evidences have suggested that neural stem cell (NSC) transplantation could facilitate functional recovery from brain insults, but their underlying mechanisms remains to be elucidated. Here, we established TBI model by an electromagnetic-controlled cortical impact device in the rats. Then, 5 μl NSCs (5.0 × 10

Indexed as

AnimalsBrain-Derived Neurotrophic FactorBrain Injuries, TraumaticCells, CulturedFemaleMaleMiceMice, KnockoutMice, TransgenicNeural Stem CellsNeuronal PlasticityRatsRats, Sprague-DawleyRecovery of FunctionStem Cell TransplantationBdnf protein, ratBrain-Derived Neurotrophic FactorBrain-derived neurotrophic factorNeural stem cell transplantationRNA knockdownSynaptophysinTraumatic brain injury

Identifiers

PMID28421542
OpenAlexW2606329317

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.