Evidence map›Paper›PMID 28421539›Full record

ArticleMolecular neurobiology2018

α-Synuclein Aggregates with β-Amyloid or Tau in Human Red Blood Cells: Correlation with Antioxidant Capability and Physical Exercise in Human Healthy Subjects.

Simona Daniele, Deborah Pietrobono, Jonathan Fusi, Caterina Iofrida, Lucia Chico, Lucia Petrozzi, Annalisa Lo Gerfo, Filippo Baldacci, Fabio Galetta, Gabriele Siciliano and 5 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Physical activity across the life course and neural biomarkers.Journal of Alzheimer's disease : JAD · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Simona Daniele *Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126, Pisa, Italy.
Deborah Pietrobono *Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126, Pisa, Italy.
Jonathan Fusi *Department of Clinical and Experimental Medicine, University of Pisa, 56120, Pisa, Italy.
Caterina IofridaDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126, Pisa, Italy.
Lucia ChicoDepartment of Clinical and Experimental Medicine, University of Pisa, 56120, Pisa, Italy.
Lucia PetrozziDepartment of Clinical and Experimental Medicine, University of Pisa, 56120, Pisa, Italy.
Annalisa Lo GerfoDepartment of Clinical and Experimental Medicine, University of Pisa, 56120, Pisa, Italy.
Filippo BaldacciDepartment of Clinical and Experimental Medicine, University of Pisa, 56120, Pisa, Italy.
Fabio GalettaDepartment of Clinical and Experimental Medicine, University of Pisa, 56120, Pisa, Italy.
Gabriele SicilianoDepartment of Clinical and Experimental Medicine, University of Pisa, 56120, Pisa, Italy.
Ubaldo BonuccelliDepartment of Clinical and Experimental Medicine, University of Pisa, 56120, Pisa, Italy.
Gino SantoroDepartment of Clinical and Experimental Medicine, University of Pisa, 56120, Pisa, Italy.
Maria Letizia TrincavelliDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126, Pisa, Italy. maria.trincavelli@unipi.it.ORCID http://orcid.org/0000-0001-8124-977X
Ferdinando FranzoniDepartment of Clinical and Experimental Medicine, University of Pisa, 56120, Pisa, Italy. ferdinando.franzoni@unipi.it.
Claudia MartiniDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126, Pisa, Italy.
University of Pisa · IT

Funding

PRA2016 539999_2015
6 · The paper itself

Abstract

Neurodegenerative disorders (NDs) are characterized by abnormal accumulation/misfolding of specific proteins, primarily α-synuclein (α-syn), β-amyloid

Indexed as

AdultAgedalpha-SynucleinAmyloid beta-PeptidesAntioxidantsBiomarkersCohort StudiesErythrocytesExerciseFemaleHealthy VolunteersHumansMaleMiddle AgedOxidative StressPeptide Fragmentsalpha-SynucleinAmyloid beta-Peptidesamyloid beta-protein (1-42)AntioxidantsBiomarkersPeptide FragmentsProtein Aggregatestau ProteinsAntioxidant capabilityNeurodegenerative diseasesPhysical exerciseProtein misfoldingTauα-Synucleinα-Synuclein heterocomplexesβ-Amyloid

Identifiers

PMID28421539
OpenAlexW2606673671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.