ArticleDocumenta ophthalmologica. Advances in ophthalmology2017
VEP and PERG in patients with multiple sclerosis, with and without a history of optic neuritis.
Article in Documenta ophthalmologica. Advances in ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 24 citations in OpenAlex.
- Evaluation of optic nerve and retinal functions in demyelinating diseases using electrophysiological tests.Documenta ophthalmologica. Advances in ophthalmology · 2026Article
- VEP Abnormalities in Treatment-Naïve CIS/Early RRMS Without Prior Optic Neuritis: Clinical, Radiological, and CSF Associations.Medicina (Kaunas, Lithuania) · 2026Article
- Functional and structural outcomes in paediatric myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): a prospective study.Documenta ophthalmologica. Advances in ophthalmology · 2026Article
- Structural and Functional Assessment of the Macular Inner Retinal Layers in Multiple Sclerosis Eyes Without History of Optic Neuropathy.Journal of clinical medicine · 2025Article
- Optic nerve involvement in patients with Lyme neuroborreliosis: an electrophysiological study.Documenta ophthalmologica. Advances in ophthalmology · 2024Article
- Topographical Correlation between Structural and Functional Impairment of the Macular Inner Retinal Layers in Multiple Sclerosis Eyes with a History of Optic Neuropathy.Journal of clinical medicine · 2023Article
- Visually Evoked Potential as Prognostic Biomarker for Neuroaxonal Damage in Multiple Sclerosis From a Multicenter Longitudinal Cohort.Neurology(R) neuroimmunology & neuroinflammation · 2023Article
- Prognostic Role of Visual Evoked Potentials in Non-Neuritic Eyes at Multiple Sclerosis Diagnosis.Journal of clinical medicine · 2023Article
- The Importance of Optical Coherence Tomography in the Diagnosis of Atypical or Subclinical Optic Neuritis: A Case Series Study.Journal of clinical medicine · 2023Article
- Relationship between optical coherence tomography angiography and visual evoked potential in patients with multiple sclerosis.Indian journal of ophthalmology · 2022Article
- Clinical electrophysiology of the optic nerve and retinal ganglion cells.Eye (London, England) · 2021Review
- Visual Dysfunction in Multiple Sclerosis and its Animal Model, Experimental Autoimmune Encephalomyelitis: a Review.Molecular neurobiology · 2021Review
- Comparison of the Structure and Function of the Retina and the Optic Nerve in Patients with a History of Multiple Sclerosis-Related Demyelinating Retrobulbar Optic Neuritis Treated and Not Treated with Systemic Steroid Therapy.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Functional Assessment of Outer and Middle Macular Layers in Multiple Sclerosis.Journal of clinical medicine · 2020Article
- Decoding PERG: A neuro-ophthalmic retinal ganglion cell function review.Current ophthalmology reports · 2019Article
- The electrophysiological assessment of visual function in Multiple Sclerosis.Clinical neurophysiology practice · 2019Review
- Colored filters enhancing visual evoked potential (VEP) response in multiple sclerosis.Journal of optometryArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeVisual electrophysiology is routinely used to detect the visual complications of multiple sclerosis, but the analysis mostly focuses on visual evoked potential (VEP) and especially the P100 component. Our goal was to analyze the components and waveform alterations of VEPs and pattern electroretinograms (PERGs) in patients with multiple sclerosis (MS) with good vision.
methodsThe main VEP and PERG components of 85 patients with MS were analyzed in two groups: 38 patients who had optic neuritis in their history (ON group) and 47 patients who had never had optic neuritis (MS group). The results were compared against a control group of 47 healthy subjects.
resultsBoth VEP and PERG alterations occurred in a greater number of patients than expected, and these alterations were not necessarily linked to ON in the history or a deterioration of visual acuity.
conclusionsBoth VEP and PERG can detect dysfunction in the visual system in MS, even if the patient has no subjective symptoms. Even if PERG is not routinely used in neuro-ophthalmology, the results suggest that PERG assessment may provide useful information describing the retinal defect in MS.
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Registered trials
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