Evidence map›Paper›PMID 28421353›Full record

ArticleAIDS and behavior2017

Phosphatidylethanol (PEth) as a Biomarker of Alcohol Consumption in HIV-Infected Young Russian Women: Comparison to Self-Report Assessments of Alcohol Use.

Andrew K Littlefield, Jennifer L Brown, Ralph J DiClemente, Polina Safonova, Jessica M Sales, Eve S Rose, Nikolay Belyakov, Vadim V Rassokhin

Abstract read
In one paragraph

Article in AIDS and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Andrew K LittlefieldDepartment of Psychological Sciences, Texas Tech University, 2500 Broadway, Lubbock, TX, 79409, USA. andrew.littlefield@ttu.edu.ORCID http://orcid.org/0000-0002-4725-1152
Jennifer L BrownAddiction Sciences Division, Department of Psychiatry & Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Ralph J DiClementeDepartment of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Polina SafonovaSaint Petersburg AIDS Center, Saint Petersburg, Russia.
Jessica M SalesDepartment of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Eve S RoseDepartment of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Nikolay BelyakovNorth-West Regional Center for Control and Prevention of AIDS, Saint Petersburg, Russia.
Vadim V RassokhinFirst Pavlov State Medical University, Saint Petersburg, Russia.
Emory University · USFirst Pavlov State Medical University of St. Petersburg · RURegional Center for Prevention and Control of AIDS and Infectious Diseases · RUTexas Tech University · USUniversity of Cincinnati Medical Center · US

Funding

Reducing Alcohol-Related HIV Risk in African American FemalesR01AA018096 · NIAAA · EMORY UNIVERSITY · PI DICLEMENTE, RALPH J, MONAHAN, JENNIFER L · 2010 to 2014
$3.8M
KIIDS: Knowing about intervention implementation in Detention SitesU01DA036233 · NIDA · EMORY UNIVERSITY · PI DICLEMENTE, RALPH J, SALES, JESSICA A · 2013 to 2017
$3.5M
Impact of Drug Use Treatment on HIV Risk Behaviors: An Integrative Data AnalysisR03DA037786 · NIDA · UNIVERSITY OF CINCINNATI · PI BROWN, JENNIFER L · 2014 to 2015
$303k
NIAAA NIH HHS R01 AA018096NIDA NIH HHS R03 DA037786NIDA NIH HHS U01 DA036233
6 · The paper itself

Abstract

Alcohol use is particularly deleterious for HIV-infected individuals and thus accurate assessment of alcohol consumption is crucial in this population. Phosphatidylethanol (PEth) provides an objective assessment of drinking and can be compared to self-reported alcohol assessments to detect underreporting. The purpose of this study was to identify underreporting and its potential predictors in an HIV-infected sample of young Russian women. The current study examined the concordance between a quantitative measure of PEth and self-reported recent alcohol consumption in a prospective sample of HIV-infected young women (N = 204) receiving medical care in Saint Petersburg, Russia. At baseline, 53% of participants who denied drinking in the prior 30 days tested positive for PEth (i.e., underreporters), although this rate decreased significantly at a three-month follow-up assessment. Further exploration did not identify consistent predictors of underreporting status. Quantitative PEth levels showed, at best, modest overlap to self-reported alcohol consumption among those reporting alcohol use (e.g., Spearman's r = 0.27 between PEth and total drinks past-30 days at baseline). Objective measures of alcohol consumption demonstrate modest overlap with self-report measures of use in HIV-infected young Russian women. Incorporating objective and quantifiable biological markers are essential for valid assessments of alcohol use.

Indexed as

Self ReportAdultAlcohol DrinkingBiomarkersFemaleGlycerophospholipidsHIV InfectionsHumansProspective StudiesRussiaBiomarkersGlycerophospholipidsphosphatidylethanolAlcohol drinkingBiomarkerHIVPhosphatidylethanol

Identifiers

PMID28421353
PMCPMC5642275
OpenAlexW2605924951

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.