ArticlePlanta2017
Regulation of CONIFERALDEHYDE 5-HYDROXYLASE expression to modulate cell wall lignin structure in rice.
Article in Planta, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 90 citations in OpenAlex.
- Advances in Genes Associated with Straw Degradation in Rice.Life (Basel, Switzerland) · 2026Review
- Using transcriptome analysis and QTL mapping to decipher the genetic basis of heterosis in potato root system.BMC plant biology · 2025Article
- OsNTL2 confers rice osmotic stress resilience through coordinated transcriptional regulation of the ASC-GSH redox cycle and cell wall biosynthesis.Stress biology · 2025Article
- Boosting photosynthesis opens new opportunities for agriculture sustainability and circular economy: The BEST-CROP research and innovation action.The Plant journal : for cell and molecular biology · 2025Review
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- Widely targeted metabolomics reveal the distribution of primary and secondary metabolites in pomegranate fruit.Food science & nutrition · 2024Article
- Metabolic engineering ofPlant biotechnology (Tokyo, Japan) · 2024Article
- Transcriptome and biochemical analyses reveal phenolic compounds-mediated flavor differences in loquat (Food chemistry: X · 2024Article
- Review
- Grass lignin: biosynthesis, biological roles, and industrial applications.Frontiers in plant science · 2024Review
- Chemical Structure Diversity and Extensive Biological Functions of Specialized Metabolites in Rice.International journal of molecular sciences · 2023Review
- Lignin, the Lignification Process, and Advanced, Lignin-Based Materials.International journal of molecular sciences · 2023Review
- Lignocellulose molecular assembly and deconstruction properties of lignin-altered rice mutants.Plant physiology · 2023Article
- Novel candidate genes for lignin structure identified through genome-wide association study of naturally varyingFrontiers in plant science · 2023Article
- Cell Wall Matrix Polysaccharides Contribute to Salt-Alkali Tolerance in Rice.International journal of molecular sciences · 2022Article
- Genome-edited rice deficient in two 4-COUMARATE:COENZYME A LIGASE genes displays diverse lignin alterations.Plant physiology · 2022Article
- An insight into microRNA biogenesis and its regulatory role in plant secondary metabolism.Plant cell reports · 2022Review
- Transcriptomic and Epigenomic Assessment Reveals Epigenetic Regulation of WRKY Genes in Response toCurrent genomics · 2022Article
- Article
- Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MAIN
conclusionRegulation of a gene encoding coniferaldehyde 5-hydroxylase leads to substantial alterations in lignin structure in rice cell walls, identifying a promising genetic engineering target for improving grass biomass utilization. The aromatic composition of lignin greatly affects utilization characteristics of lignocellulosic biomass and, therefore, has been one of the primary targets of cell wall engineering studies. Limited information is, however, available regarding lignin modifications in monocotyledonous grasses, despite the fact that grass lignocelluloses have a great potential for feedstocks of biofuel production and various biorefinery applications. Here, we report that manipulation of a gene encoding coniferaldehyde 5-hydroxylase (CAld5H, or ferulate 5-hydroxylase, F5H) leads to substantial alterations in syringyl (S)/guaiacyl (G) lignin aromatic composition in rice (Oryza sativa), a major model grass and commercially important crop. Among three CAld5H genes identified in rice, OsCAld5H1 (CYP84A5) appeared to be predominantly expressed in lignin-producing rice vegetative tissues. Down-regulation of OsCAld5H1 produced altered lignins largely enriched in G units, whereas up-regulation of OsCAld5H1 resulted in lignins enriched in S units, as revealed by a series of wet-chemical and NMR structural analyses. Our data collectively demonstrate that OsCAld5H1 expression is a major factor controlling S/G lignin composition in rice cell walls. Given that S/G lignin composition affects various biomass properties, we contemplate that manipulation of CAld5H gene expression represents a promising strategy to upgrade grass biomass for biorefinery applications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.