Evidence map›Paper›PMID 28421279›Full record

ReviewCurrent genetics2017

Sporulation: how to survive on planet Earth (and beyond).

Mingwei Huang, Christina M Hull

Abstract readReview
In one paragraph

Review in Current genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Milestones in the development ofJournal of bacteriology · 2025
    Review
  8. Insights from Mass Spectrometry-Based Proteomics onJournal of fungi (Basel, Switzerland) · 2025
    Review
  9. Article
  10. Macromolecular Crowding in Cell Stress and Death.Sub-cellular biochemistry · 2025
    Review
  11. Review
  12. The megaplasmid pCER270 ofApplied and environmental microbiology · 2024
    Article
  13. Review
  14. Assessing the Presence ofSensors (Basel, Switzerland) · 2024
    Article
  15. Review
  16. Biogenesis, germination, and pathogenesis ofMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mingwei HuangDepartment of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, 1135 Biochemistry Building, 420 Henry Mall, Madison, WI, 53706, USA.
Christina M HullDepartment of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, 1135 Biochemistry Building, 420 Henry Mall, Madison, WI, 53706, USA. cmhull@wisc.edu.

Funding

Pathogenesis of Cryptococcus SporesR01AI089370 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI HULL, CHRISTINA M · 2010 to 2014
$1.7M
Hartwell Foundation Individual Biomedical Research AwardNational Institutes of Health R01 grant AI089370NIAID NIH HHS R01 AI089370
6 · The paper itself

Abstract

Sporulation is a strategy widely utilized by a wide variety of organisms to adapt to changes in their individual environmental niches and survive in time and/or space until they encounter conditions acceptable for vegetative growth. The spores produced by bacteria have been the subjects of extensive studies, and several systems such as Bacillus subtilis have provided ample opportunities to understand the molecular basis of spore biogenesis and germination. In contrast, the spores of other microbes, such as fungi, are relatively poorly understood. Studies of sporulation in model systems such as Saccharomyces cerevisiae and Aspergillus nidulans have established a basis for investigating eukaryotic spores, but very little is known at the molecular level about how spores function. This is especially true among the spores of human fungal pathogens such as the most common cause of fatal fungal disease, Cryptococcus neoformans. Recent proteomic studies are helping to determine the molecular mechanisms by which pathogenic fungal spores are formed, persist and germinate into actively growing agents of human disease.

Indexed as

Adaptation, BiologicalBacterial Physiological PhenomenaFungiSpores, BacterialSpores, FungalFungal pathogenesisGerminationProteomicsSexual developmentSpores

Identifiers

PMID28421279
PMCPMC5647196

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.