Evidence map›Paper›PMID 28421185›Full record

ArticleFrontiers in cardiovascular medicine2017

Changes in Composition of the Gut Bacterial Microbiome after Fecal Microbiota Transplantation for Recurrent

Kyle L Flannigan, Taylor Rajbar, Andrew Moffat, Leanna S McKenzie, Frank Dicke, Kevin Rioux, Matthew L Workentine, Thomas J Louie, Simon A Hirota, Steven C Greenway

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in cardiovascular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Clostridioides difficile Infections: Prevention and Treatment Strategies.Advances in experimental medicine and biology · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Efficacy of Fecal Microbiota Transplantation for Clostridium difficile Infection in Children.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Kyle L FlanniganDepartment of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Taylor RajbarDepartment of Paediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Andrew MoffatDepartment of Paediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Leanna S McKenzieDepartment of Paediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Frank DickeDepartment of Paediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Kevin RiouxDepartment of Immunology, Microbiology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Matthew L WorkentineFaculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada.
Thomas J LouieDepartment of Immunology, Microbiology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Simon A HirotaDepartment of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Steven C GreenwayDepartment of Paediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
University of Calgary · CAAlberta Children's Hospital · CALibin Cardiovascular Institute of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The microbiome is increasingly recognized as an important influence on human health and many of the comorbidities that affect patients after solid organ transplantation (SOT) have been shown to involve changes in gut bacterial populations. Thus, microbiome changes in an individual patient may have important health implications after SOT but this area remains understudied. We describe changes in the composition of the fecal microbiome from a pediatric heart transplant recipient before and >2.5 years after he underwent repeated fecal microbiota transplantation (FMT) for recurrent

Indexed as

fecal microbiota transplantheart transplantationimmunosuppressionmicrobiomepediatric

Identifiers

PMID28421185
PMCPMC5378704
OpenAlexW2604792730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.