Evidence map›Paper›PMID 28421060›Full record

ArticleFrontiers in microbiology2017

The Heme Metabolite Carbon Monoxide Facilitates KSHV Infection by Inhibiting TLR4 Signaling in Endothelial Cells.

Sara Botto, Jean K Gustin, Ashlee V Moses

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sara BottoVaccine and Gene Therapy Institute, Oregon Health and Science University, PortlandOR, USA.
Jean K GustinVaccine and Gene Therapy Institute, Oregon Health and Science University, PortlandOR, USA.
Ashlee V MosesVaccine and Gene Therapy Institute, Oregon Health and Science University, PortlandOR, USA.
Oregon Health & Science University · US

Funding

Heme oxygenase-1 as a tumor factor and therapeutic target for Kaposi sarcomaR01CA179921 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MOSES, ASHLEE V. · 2015 to 2019
$1.9M
NCI NIH HHS R01 CA179921
6 · The paper itself

Abstract

Kaposi sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi sarcoma (KS) and certain rare B cell lymphoproliferative disorders. KSHV infection of endothelial cells (EC)

Indexed as

carbon monoxideCOheme oxygenase-1HO-1innate immunityKSHVTLR4

Identifiers

PMID28421060
PMCPMC5376558
OpenAlexW2599850236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.