ArticleFrontiers in neurology2017
Orthostatic Hypotension Predicts Cognitive Impairment in the Elderly: Findings from a Cohort Study.
Article in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- Comparison of Remimazolam and Propofol on Post-Induction Hypotension in Elderly Hypertensive Patients: A Randomized Controlled Trial.Drug design, development and therapy · 2025Trial
- Association of Potentially Inappropriate Medications and Geriatric Nutritional Risk Index with Frailty in Elderly Patients with Ischemic Heart Disease.Diagnostics (Basel, Switzerland) · 2026Article
- The relationship between orthostatic hypotension and cognitive impairment in Parkinson's disease: a systematic review and meta-analysis.Frontiers in medicine · 2025Review
- A novel oral medicated jelly for enhancement of etilefrine hydrochloride bioavailability:Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022Article
- Orthostatic hypotension in older people: considerations, diagnosis and management.Clinical medicine (London, England) · 2021Review
- Impact of Cardiovascular Hemodynamics on Cognitive Aging.Arteriosclerosis, thrombosis, and vascular biology · 2021Review
- Orthostatic hypotension and dementia incidence: links and implications.Neuropsychiatric disease and treatment · 2019Article
- Association between Orthostatic Hypotension and Frailty in Hospitalized Older Patients: a Geriatric Syndrome More Than a Cardiovascular Condition.The journal of nutrition, health & aging · 2019Observational
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOrthostatic hypotension (OH) is a known risk factor for cerebral ischemia, but its correlation with cognitive impairment (CI) is not well established.
objectiveThe aim of this study is to explore the relationship between OH and CI in the elderly.
methodsThe study group consisted of 44 OH patients who presented with drowsiness, vertigo, and fatigue between January 2009 and December 2011 (OH group). Eighty-eight healthy elderly were paired with those in the OH group in a 1:2 based on their education levels (NOH group). Baseline sociodemographic information and cognition-related measures were collected for both groups. Cognitive function was assessed 4 years later using MMSE.
resultsThe overall incidence of CI was 14.0% among the 114 subjects who completed the follow-up assessment. There was a significant difference in the incidence of CI between the OH group (23.7%) and the NOH group (9.2%) (χ
conclusionOH can lead to CI. We suggest that future studies, with a larger sample size, use OH exposure time instead of OH exposure population to verify the conclusion of this study.
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Registered trials
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