Evidence map›Paper›PMID 28421031›Full record

ArticleFrontiers in neurology2017

Fatal Outcome of European Tick-borne Encephalitis after Vaccine Failure.

Parham Sendi, Cédric Hirzel, Stefan Pfister, Rahel Ackermann-Gäumann, Denis Grandgirard, Ekkehard Hewer, Arto C Nirkko

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Parham SendiInstitute for Infectious Diseases, University of Bern, Bern, Switzerland.
Cédric HirzelBern University Hospital, Department of Infectious Diseases, Bern, Switzerland.
Stefan PfisterInstitute for Infectious Diseases, University of Bern, Bern, Switzerland.
Rahel Ackermann-GäumannSpiez Laboratory, Swiss National Reference Centre for Tick-transmitted Diseases, Federal Office for Civil Protection, Spiez, Switzerland.
Denis GrandgirardInstitute for Infectious Diseases, University of Bern, Bern, Switzerland.
Ekkehard HewerInstitute of Pathology, University of Bern, Bern, Switzerland.
Arto C NirkkoDepartment of Neurology, Schlaf-Wach-Epilepsie-Zentrum (SWEZ), University of Bern, Bern, Switzerland.
University of Bern · CHSpiez Laboratory · CHUniversity Hospital of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tick-borne encephalitis is a viral disease affecting the central nervous system. It is endemic in Switzerland with 200-250 notified cases annually. Active immunization is effective for persons in all age groups. Vaccine failure is rare, in particular after a completed vaccination course. Here, we describe the case of 67-year-old man with a fatal outcome despite vaccination. The diagnosis was confirmed by extensive postmortem analyses. The diagnostic challenges of vaccine failure in tick-borne encephalitis and the dynamics of the immune response in vaccination breakthrough are discussed.

Indexed as

flavivirustick-borne encephalitistick-borne encephalitis vaccinevaccine efficacyvaccine failure

Identifiers

PMID28421031
PMCPMC5377060
OpenAlexW2605254618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.