Evidence map›Paper›PMID 28420995›Full record

ArticleFrontiers in pharmacology2017

Quantum Dots-siRNA Nanoplexes for Gene Silencing in Central Nervous System Tumor Cells.

Guimiao Lin, Ting Chen, Jinyun Zou, Yucheng Wang, Xiaomei Wang, Jiefeng Li, Qijun Huang, Zicai Fu, Yingying Zhao, Marie Chia-Mi Lin and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Cyclic Peptide-Gadolinium Nanocomplexes as siRNA Delivery Tools.Pharmaceuticals (Basel, Switzerland) · 2021
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Nanomedicine for Glioblastoma Therapy: Novel Insights and Future Perspectives.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Guimiao LinDepartment of Physiology, School of Basic Medical Sciences, Shenzhen University Health Sciences CenterShenzhen, China.
Ting ChenDepartment of Physiology, School of Basic Medical Sciences, Shenzhen University Health Sciences CenterShenzhen, China.
Jinyun ZouDepartment of Physiology, School of Basic Medical Sciences, Shenzhen University Health Sciences CenterShenzhen, China.
Yucheng WangSchool of Electrical and Electronic Engineering, Nanyang Technological UniversitySingapore, Singapore.
Xiaomei WangDepartment of Physiology, School of Basic Medical Sciences, Shenzhen University Health Sciences CenterShenzhen, China.
Jiefeng LiDepartment of Physiology, School of Basic Medical Sciences, Shenzhen University Health Sciences CenterShenzhen, China.
Qijun HuangDepartment of Physiology, School of Basic Medical Sciences, Shenzhen University Health Sciences CenterShenzhen, China.
Zicai FuDepartment of Physiology, School of Basic Medical Sciences, Shenzhen University Health Sciences CenterShenzhen, China.
Yingying ZhaoDepartment of Physiology, School of Basic Medical Sciences, Shenzhen University Health Sciences CenterShenzhen, China.
Marie Chia-Mi LinDepartment of Physiology, School of Basic Medical Sciences, Shenzhen University Health Sciences CenterShenzhen, China.
Gaixia XuKey Laboratory of Optoelectronics Devices and Systems of Ministry of Education/Guangdong Province, College of Optoelectronic Engineering, Shenzhen UniversityShenzhen, China.
Ken-Tye YongSchool of Electrical and Electronic Engineering, Nanyang Technological UniversitySingapore, Singapore.
Shenzhen University Health Science Center · CNNanyang Technological University · SGShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA interfering (RNAi) using short interfering RNA (siRNA) is becoming a promising approach for cancer gene therapy. However, owing to the lack of safe and efficient carriers, the application of RNAi for clinical use is still very limited. In this study, we have developed cadmium sulphoselenide/Zinc sulfide quantum dots (CdSSe/ZnS QDs)-based nanocarriers for

Indexed as

gene deliveryglioblastomahuman telomerase reverse transcriptasequantum dotsRNA interfering

Identifiers

PMID28420995
PMCPMC5378761
OpenAlexW2604655546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.