ArticleFrontiers in aging neuroscience2017
Mapping Dorsal and Ventral Caudate in Older Adults: Method and Validation.
Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The convergent neuroscience of Christian prayer and attachment relationships in the context of mental health: a systematic review.Frontiers in psychology · 2025Pooled it
- A Comprehensive Meta-analysis on Short-term and Working Memory Dysfunction in Parkinson's Disease.Neuropsychology review · 2021Pooled it
- Chronic Co-administration of Methylphenidate and Fluoxetine Reduces Striatal NMDA Receptor Binding in Adolescent Rats.Neurochemical research · 2026Article
- Brain-clinical signatures of basal ganglia-related dysfunctional reorganisation in Parkinson's disease.EBioMedicine · 2025Article
- Cerebellar gray matter atrophy and altered structural covariance networks are associated with cognitive impairment in type 2 diabetes mellitus.Frontiers in neurology · 2025Article
- Dedifferentiation of caudate functional organization is linked to reduced D1 dopamine receptor availability and poorer memory function in aging.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- A distinctive subcortical functional connectivity pattern linking negative affect and treatment outcome in major depressive disorder.Translational psychiatry · 2024Article
- Caudate functional networks influence brain structural changes with aging.Brain communications · 2024Article
- Phytocannabinoids as Potential Multitargeting Neuroprotectants in Alzheimer's Disease.Current drug research reviews · 2024Review
- Altered structural covariance of locus coeruleus in individuals with significant memory concern and patients with mild cognitive impairment.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Abnormal whole-brain voxelwise structure-function coupling and its association with cognitive dysfunction in patients with different cerebral small vessel disease burdens.Frontiers in aging neuroscience · 2023Article
- Resting-State Brain Activity Dysfunctions in Schizophrenia and Their Associations with Negative Symptom Domains: An fMRI Study.Brain sciences · 2023Article
- Altered functional connectivity of the right caudate nucleus in chronic migraine: a resting-state fMRI study.The journal of headache and pain · 2022Article
- Dual-targeted repetitive transcranial magnetic stimulation modulates brain functional network connectivity to improve cognition in mild cognitive impairment patients.Frontiers in physiology · 2022Article
- Topographic organization of the human caudate functional connectivity and age-related changes with resting-state fMRI.Frontiers in systems neuroscience · 2022Article
- Fractional amplitude of low-frequency fluctuation in patients with neovascular glaucoma: a resting-state functional magnetic resonance imaging study.Quantitative imaging in medicine and surgery · 2021Article
- Resting State Hypoconnectivity of Reward Networks in Binge Eating Disorder.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Dog-human social relationship: representation of human face familiarity and emotions in the dog brain.Animal cognition · 2021Article
- Article
- The Interaction Between Caudate Nucleus and Regions Within the Theory of Mind Network as a Neural Basis for Social Intelligence.Frontiers in neural circuits · 2021Article
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Authors and funding
6 authors.
Funding
Abstract
The caudate nucleus plays important roles in cognition and affect. Depending on associated connectivity and function, the caudate can be further divided into dorsal and ventral aspects. Dorsal caudate, highly connected to dorsolateral prefrontal cortex (DLPFC), is implicated in executive function and working memory; ventral caudate, more interconnected with the limbic system, is implicated in affective functions such as pain processing. Clinically, certain brain disorders are known to differentially impact dorsal and ventral caudate. Thus, precise parcellation of caudate has both basic and clinical neuroscience significance. In young adults, past work has combined resting-state fMRI functional connectivity with clustering algorithms to define dorsal and ventral caudate. Whether the same approach is effective in older adults and how to validate the parcellation results have not been considered. We addressed these problems by obtaining resting-state fMRI data from 56 older non-demented adults (age: 69.07 ± 5.92 years and MOCA: 25.71 ± 2.46) along with a battery of cognitive and clinical assessments. Connectivity from each voxel of caudate to the rest of the brain was computed using cross correlation. Applying the K-means clustering algorithm to the connectivity patterns with
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