Evidence map›Paper›PMID 28420813›Full record

ArticleJournal of clinical and experimental hematopathology : JCEH2017

Establishment of cell lines from adult T-cell leukemia cells dependent on negatively charged polymers.

Yoshitoyo Kagami, Susumu Uchiyama, Harumi Kato, Yasutaka Okada, Masao Seto, Tomohiro Kinoshita

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and experimental hematopathology : JCEH, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Yoshitoyo KagamiDepartment of Hematology, Toyota Kosei Hospital.
Susumu UchiyamaDepartment of Biotechnology, Graduate School of Engineering, Osaka University.
Harumi KatoDepartment of Hematology and Cell Therapy, Aichi Cancer Center Hospital.
Yasutaka OkadaDepartment of Clinical Laboratories, Aichi Cancer Center Hospital.
Masao SetoDepartment of Pathology, Kurume University School of Medicine.
Tomohiro KinoshitaDepartment of Hematology and Cell Therapy, Aichi Cancer Center Hospital.
Aichi Cancer Center · JPKurume University · JPOsaka University · JPToyota Kosei Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growing adult T-cell leukemia/lymphoma (ATLL) cells in vitro is difficult. Here, we examined the effects of static electricity in the culture medium on the proliferation of ATLL cells. Six out of 10 ATLL cells did not proliferate in vitro and thus had to be cultured in a medium containing negatively charged polymers. In the presence of poly-γ-glutamic acid (PGA) or chondroitin sulfate (CDR), cell lines (HKOX3-PGA, HKOX3-CDR) were established from the same single ATLL case using interleukin (IL)-2, IL-4, and feeder cells expressing OX40L (OX40L

Indexed as

Cell Line, TumorPolymersAdultBiomarkersCell Culture TechniquesCell ProliferationCytokinesDendritic Cells, FollicularGene Rearrangement, gamma-Chain T-Cell Antigen ReceptorHumansHuman T-lymphotropic virus 1ImmunophenotypingLeukemia-Lymphoma, Adult T-CellPhenotypeReceptors, Antigen, T-Cell, gamma-deltaVirus IntegrationBiomarkersCytokinesPolymersReceptors, Antigen, T-Cell, gamma-deltaAdult T-cell leukemia/lymphomaCell lineCharged polymerFollicular dendritic cellInterleukin

Identifiers

PMID28420813
PMCPMC6144268
OpenAlexW2606488810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.