Trial reportProceedings of the National Academy of Sciences of the United States of America2017
Reconstructing the spectrotemporal modulations of real-life sounds from fMRI response patterns.
Trial report in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed.
- The shape of attention reflects flexible filtering of natural speech modulations.Communications biology · 2026Article
- Individual Brain Charting: fifth release of high-resolution fMRI data for cognitive mapping.Scientific data · 2026Article
- Deep Sound Synthesis Matched to Brain Activity Recapitulates Preferential Responses to Speech and Music.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Article
- Text-to-music generation models capture musical semantic representations in the human brain.Nature communications · 2025Article
- Auditory Cortical Gradients Integrate Bottom-Up and Top-Down Structure During Natural Sound Categorisation.bioRxiv : the preprint server for biology · 2025Article
- Natural sounds can be reconstructed from human neuroimaging data using deep neural network representation.PLoS biology · 2025Article
- A hierarchy of processing complexity and timescales for natural sounds in the human auditory cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Ultra high density imaging arrays in diffuse optical tomography for human brain mapping improve image quality and decoding performance.Scientific reports · 2025Article
- Speech prosody enhances the neural processing of syntax.Communications biology · 2024Article
- Impaired Cortical Tracking of Speech in Children with Developmental Language Disorder.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- The human auditory system uses amplitude modulation to distinguish music from speech.PLoS biology · 2024Article
- Linguistic modulation of the neural encoding of phonemes.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Encoding of melody in the human auditory cortex.Science advances · 2024Article
- The Auditory Agnosias: a Short Review of Neurofunctional Evidence.Current neurology and neuroscience reports · 2023Review
- Selective attention sharpens population receptive fields in human auditory cortex.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Intermediate acoustic-to-semantic representations link behavioral and neural responses to natural sounds.Nature neuroscience · 2023Article
- A modality-independent proto-organization of human multisensory areas.Nature human behaviour · 2023Article
- The Representation of Time Windows in Primate Auditory Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Speech Computations of the Human Superior Temporal Gyrus.Annual review of psychology · 2022Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Ethological views of brain functioning suggest that sound representations and computations in the auditory neural system are optimized finely to process and discriminate behaviorally relevant acoustic features and sounds (e.g., spectrotemporal modulations in the songs of zebra finches). Here, we show that modeling of neural sound representations in terms of frequency-specific spectrotemporal modulations enables accurate and specific reconstruction of real-life sounds from high-resolution functional magnetic resonance imaging (fMRI) response patterns in the human auditory cortex. Region-based analyses indicated that response patterns in separate portions of the auditory cortex are informative of distinctive sets of spectrotemporal modulations. Most relevantly, results revealed that in early auditory regions, and progressively more in surrounding regions, temporal modulations in a range relevant for speech analysis (∼2-4 Hz) were reconstructed more faithfully than other temporal modulations. In early auditory regions, this effect was frequency-dependent and only present for lower frequencies (<∼2 kHz), whereas for higher frequencies, reconstruction accuracy was higher for faster temporal modulations. Further analyses suggested that auditory cortical processing optimized for the fine-grained discrimination of speech and vocal sounds underlies this enhanced reconstruction accuracy. In sum, the present study introduces an approach to embed models of neural sound representations in the analysis of fMRI response patterns. Furthermore, it reveals that, in the human brain, even general purpose and fundamental neural processing mechanisms are shaped by the physical features of real-world stimuli that are most relevant for behavior (i.e., speech, voice).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.