Evidence map›Paper›PMID 28420711›Full record

ArticleDevelopment (Cambridge, England)2017

Excitatory neurons sculpt GABAergic neuronal connectivity in the

Belinda Barbagallo, Alison Philbrook, Denis Touroutine, Navonil Banerjee, Devyn Oliver, Christopher M Lambert, Michael M Francis

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  4. Transsynaptic linking of calcium channels and postsynaptic receptors at a dyadic synapse.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Molecular and Cellular Mechanisms of Motor Circuit Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  8. Article
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  11. Article
  12. Article
  13. Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Belinda BarbagalloDepartment of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Alison PhilbrookDepartment of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Denis TouroutineDepartment of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA.ORCID 0000-0002-3142-0273
Navonil BanerjeeDepartment of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Devyn OliverDepartment of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Christopher M LambertDepartment of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Michael M FrancisDepartment of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA michael.francis@umassmed.edu.ORCID 0000-0002-8076-6668
University of Massachusetts Chan Medical School · US

Funding

Molecular Analysis of Neural Circuit Excitation and InhibitionR01NS064263 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FRANCIS, MICHAEL M · 2009 to 2025
$5.5M
Molecular regulation of nicotinic acetylcholine receptorsF31DA038399 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI PHILBROOK, ALISON · 2015 to 2017
$91k
Identifying excitotoxic mechanisms in a C. elegans model of axon destabilizationF31NS076326 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BARBAGALLO, BELINDA · 2011 to 2013
$86k
NIDA NIH HHS F31 DA038399NINDS NIH HHS F31 NS076326NINDS NIH HHS R01 NS064263
6 · The paper itself

Abstract

Establishing and maintaining the appropriate number of GABA synapses is key for balancing excitation and inhibition in the nervous system, though we have only a limited understanding of the mechanisms controlling GABA circuit connectivity. Here, we show that disrupting cholinergic innervation of GABAergic neurons in the

Indexed as

Synaptic TransmissionAnimalsAnimals, Genetically ModifiedBrainCaenorhabditis elegansCholinergic NeuronsGABAergic NeuronsMotor NeuronsNerve NetNeurogenesisNeuromuscular JunctionSignal TransductionSynapsesE/I balanceGABA synapseNeural circuitNeural development

Identifiers

PMID28420711
PMCPMC5450832
OpenAlexW2607382605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.