Evidence map›Paper›PMID 28420704›Full record

ArticleJournal of lipid research2017

Influence of HDL particles on cell-cholesterol efflux under various pathological conditions.

Bela F Asztalos, Katalin V Horvath, Michael Mehan, Yuya Yokota, Ernst J Schaefer

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  8. Review
  9. Review
  10. Article
  11. Fish-Derived Omega-3 Fatty Acids: Guardians of High-Density Lipoprotein?Journal of atherosclerosis and thrombosis · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. ABCA1, ABCG1, and Cholesterol Homeostasis.Advances in experimental medicine and biology · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Advances in HDL: Much More than Lipid Transporters.International journal of molecular sciences · 2020
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bela F AsztalosCardiovascular Nutrition Laboratory, Human Nutrition Research Center on Aging at Tufts University, Boston, MA bela.asztalos@tufts.edu.
Katalin V HorvathCardiovascular Nutrition Laboratory, Human Nutrition Research Center on Aging at Tufts University, Boston, MA.
Michael MehanBoston Heart Diagnostics, Framingham, MA.
Yuya YokotaCardiovascular Nutrition Laboratory, Human Nutrition Research Center on Aging at Tufts University, Boston, MA.
Ernst J SchaeferCardiovascular Nutrition Laboratory, Human Nutrition Research Center on Aging at Tufts University, Boston, MA.
Tufts University · US

Funding

HDL Composition/Function and Coronary Plaque FormationR01HL117933 · NHLBI · TUFTS UNIVERSITY BOSTON · PI ASZTALOS, BELA F · 2014 to 2017
$2.0M
NHLBI NIH HHS R01 HL117933
6 · The paper itself

Abstract

It has been reported that low cell-cholesterol efflux capacity (CEC) of HDL is an independent risk factor for CVD. To better understand CEC regulation, we measured ABCA1- and scavenger receptor class B type I (SR-BI)-dependent cell-cholesterol efflux, HDL anti-oxidative capacity, HDL particles, lipids, and inflammatory- and oxidative-stress markers in 122 subjects with elevated plasma levels of triglyceride (TG), serum amyloid A (SAA), fibrinogen, myeloperoxidase (MPO), or β-sitosterol and in 146 controls. In controls, there were strong positive correlations between ABCA1-dependent cholesterol efflux and small preβ-1 concentrations (

Indexed as

AntioxidantsATP Binding Cassette Transporter 1Biological TransportCD36 AntigensCholesterol, HDLFemaleFibrinogenHumansMaleMiddle AgedPeroxidaseSerum Amyloid A ProteinSitosterolsTriglyceridesAntioxidantsATP Binding Cassette Transporter 1CD36 AntigensCholesterol, HDLFibrinogengamma-sitosterolPeroxidaseSerum Amyloid A ProteinSitosterolsTriglyceridesadenosine triphosphate binding cassette transporter A1apolipoprotein A-Icardiovascular disease riskpreβ-1scavenger receptor class B type I

Identifiers

PMID28420704
PMCPMC5454514
OpenAlexW2605997656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.