Evidence map›Paper›PMID 28420693›Full record

ReviewFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

Modulation of innate immunity of patients with Alzheimer's disease by omega-3 fatty acids.

Milan Fiala, Gijs Kooij, Karen Wagner, Bruce Hammock, Matteo Pellegrini

Open access · bronzeAbstract readReview
In one paragraph

Review in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  14. Article
  15. Neurovascular and immune mechanisms that regulate postoperative delirium superimposed on dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2020
    Article
  16. Article
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  18. Elovanoids counteract oligomeric β-amyloid-induced gene expression and protect photoreceptors.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Milan FialaDepartment of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, California, USA; mfiala@ucla.edu.
Gijs KooijDepartment of Molecular Cell Biology and Immunology, Vrije Universiteit (VU) Medical Center, Multiple Sclerosis Center Amsterdam, Amsterdam, The Netherlands.
Karen WagnerDepartment of Entomology, University of California, Davis, Davis, California, USA.
Bruce HammockDepartment of Entomology, University of California, Davis, Davis, California, USA.
Matteo PellegriniDepartment of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, California, USA.
University of California, Davis · USUniversity of California, Los Angeles · USHarvard University · US

Funding

HYDROLYTIC ENZYMES IN THE METABOLISM OF TOXINSR01ES002710 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI HAMMOCK, BRUCE D · 1985 to 2018
$4.0M
NIEHS NIH HHS R01 ES002710
6 · The paper itself

Abstract

The innate immune system of patients with Alzheimer's disease and mild cognitive impairment (MCI) is deregulated with highly increased or decreased transcription of inflammatory genes and consistently depressed phagocytosis of amyloid-β

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesFatty Acids, Omega-3HumansImmunity, InnateAmyloid beta-PeptidesFatty Acids, Omega-3

Identifiers

PMID28420693
PMCPMC5503712
OpenAlexW2607287977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.