Evidence map›Paper›PMID 28420350›Full record

ArticleBMC infectious diseases2017

Trends in baseline CD4 cell counts and risk factors for late antiretroviral therapy initiation among HIV-positive patients in Shanghai, a retrospective cross-sectional study.

Jianjun Sun, Li Liu, Jiayin Shen, Panpan Chen, Hongzhou Lu

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jianjun SunDepartment of Infectious Diseases, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China.ORCID 0000-0001-5780-5334
Li LiuDepartment of Infectious Diseases, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China.
Jiayin ShenDepartment of Infectious Diseases, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China.
Panpan ChenPudong New Area Center for Disease Control and Prevention, Shanghai, 200136, China.
Hongzhou LuDepartment of Infectious Diseases, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China. luhongzhou@fudan.edu.cn.
Shanghai Public Health Clinical Center · CNShanghai Medical College of Fudan University · CNShanghai Municipal Center For Disease Control Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundsThere are few studies focus on the factors underlying the late initiation of ART in China. We analyzed the trends in the median CD4 cell counts among different patient groups over time and the risk factors for the late initiation of ART in Shanghai, China.

methodsA retrospective cross-sectional survey was made in the Department of Infectious Disease of Shanghai Public Health Clinical Center which is a designated diagnosis and treatment center for HIV-positive patients in Shanghai during the period of January 1st, 2008--June 30th, 2014. Late ART initiation was defined as a CD4 cell count <200 cells/mm

resultsA total of 3796 patients were analyzed in this study, with a median baseline CD4 cell count of 205 cells/mm

conclusionsNotable improvements were made in the median CD4 cell count at ART initiation and the proportion of late ART initiation from 2008 to 2014. However, persons with high risk of HIV exposure who are male, older even heterosexual orientation should be given more opportunities to receive frequently screening, earlier diagnoses and timely treatment.

Indexed as

AdolescentAdultAgedAged, 80 and overAnti-Retroviral AgentsCD4 Lymphocyte CountChinaCross-Sectional StudiesFemaleHeterosexualityHIV InfectionsHIV SeropositivityHumansLogistic ModelsMaleMiddle AgedAnti-Retroviral AgentsBaselineCD4 cell countsHIV infectionLate ART initiationRisk factorsTrends

Identifiers

PMID28420350
PMCPMC5395868
OpenAlexW2606910832

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.